Interactor 1: SPTA1 (P02549)
Spectrin alpha chain, erythrocytic 1 (Erythroid alpha-spectrin)
Gene: SPTA1

Interactor 2: SPTB2 (Q01082)
Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1)
Gene: SPTBN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.692

The method score is based on:

Property Details
Experiments 12820899
Identification Methods pull down, surface plasmon resonance
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CH~EFhand_Ca_insen, EFhand_Ca_insen~Spectrin, CH~Spectrin, Spectrin~Spectrin
Common GO terms GO:0005200 - structural constituent of cytoskeleton
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007009 - plasma membrane organization
GO:0008091 - spectrin
and 8 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 2419
Hs

1 2364
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Dm
+ Rn
+ Dm
+ Hs
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024