Interactor 1: SPTA1 (P02549)
Spectrin alpha chain, erythrocytic 1 (Erythroid alpha-spectrin)
Gene: SPTA1

Interactor 2: PLEC (Q15149)
Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1)
Gene: PLEC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 3027087
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CH~EFhand_Ca_insen, CH~Spectrin, SH3_10~Spectrin
Common GO terms GO:0005200 - structural constituent of cytoskeleton
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0030424 - axon
GO:0051015 - actin filament binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 2419
Hs

1 4684
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Dm
+ Mm
+ Rn
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Mm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024