HitPredict

Interactor 1: SPTA1 (P02549)
Spectrin alpha chain, erythrocytic 1 (Erythroid alpha-spectrin)
Gene: SPTA1

Interactor 2: CP250 (Q9BV73)
Centrosome-associated protein CEP250 (250 kDa centrosomal protein) (Cep250) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Centrosomal protein 2)
Gene: CEP250

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2419 Hs			1 2442
+	Hs
		360644 SPTA1_HUMAN (1-2419): 8.06e-180: 613: 100.00		PLEC_HUMAN (3-1489): 1.72e-44: 181: 13.02
+	Hs
		969580 CENPE_HUMAN (626-2397): 1.4e-57: 224: 10.42		CENPE_HUMAN (1-1454): 3.09e-50: 200: 9.53
+	Hs
		1034577 GOGB1_HUMAN (818-2397): 1.05e-41: 172: 9.47		GOGA4_HUMAN (3-1824): 1.71e-65: 250: 11.17
+	Hs
		969584 SPTN1_HUMAN (2-1574): 6.04e-39: 162: 16.14		CENPE_HUMAN (1-1454): 3.09e-50: 200: 9.53
+	Hs
		1068536 PLEC_HUMAN (2-1504): 2.23e-43: 177: 9.63		PLEC_HUMAN (3-1489): 1.72e-44: 181: 13.02
+	Dm
		527099 SPTCA_DROME (12-1728): 5.69e-51: 202: 19.75		LVA_DROME (1160-2442): 1.45e-33: 145: 12.08
+	Hs
		1045418 SPTN1_HUMAN (2-1574): 6.04e-39: 162: 16.14		PLEC_HUMAN (3-1489): 1.72e-44: 181: 13.02
+	Dm
		962674 SPTCB_DROME (7-1114): 3.65e-45: 183: 16.37		LVA_DROME (1160-2442): 1.45e-33: 145: 12.08
+	Hs
		828575 CENPE_HUMAN (626-2397): 1.4e-57: 224: 10.42		CENPF_HUMAN (1746-2440): 6.7e-19: 96.9: 11.02
+	Hs
		522612 SPTN1_HUMAN (2-1574): 6.04e-39: 162: 16.14		MYH7_HUMAN (2-831): 2.26e-36: 154: 12.28
+	Hs
		1059212 GOGB1_HUMAN (818-2397): 1.05e-41: 172: 9.47		GOGB1_HUMAN (1634-2442): 3.53e-19: 97.7: 11.58
+	Hs
		148339 ACTN1_HUMAN (1927-2418): 6.41e-50: 195: 26.84		CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55
+	Hs
		1068617 PLEC_HUMAN (2-1504): 2.23e-43: 177: 9.63		MY18A_HUMAN (1737-2312): 8.46e-11: 70.1: 21.19
+	Hs
		148841 PLEC_HUMAN (2-1504): 2.23e-43: 177: 9.63		CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55
+	Hs
		1045471 SPTN1_HUMAN (2-1574): 6.04e-39: 162: 16.14		MY18A_HUMAN (1737-2312): 8.46e-11: 70.1: 21.19
+	Hs
		148786 SPTN1_HUMAN (2-1574): 6.04e-39: 162: 16.14		CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55
+	Hs
		148330 SPTB1_HUMAN (1158-2357): 1.16e-37: 158: 17.37		CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55
+	Hs
		149277 SPTN4_HUMAN (4-762): 6.94e-37: 156: 19.50		CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55
+	Hs
		164647 SPTN2_HUMAN (1474-2371): 7.55e-25: 116: 16.03		MY18A_HUMAN (1737-2312): 8.46e-11: 70.1: 21.19
+	Hs
		148142 SPTN2_HUMAN (1474-2371): 7.55e-25: 116: 16.03		CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55