HitPredict

Interactor 1: TNNC2 (P02585)
Troponin C, skeletal muscle
Gene: TNNC2

Interactor 2: IQGA1 (P46940)
Ras GTPase-activating-like protein IQGAP1 (p195)
Gene: IQGAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	CH~EF-hand_7, EF-hand_7~IQ
Common GO terms	GO:0005509 - calcium ion binding GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 160 Hs			1 1657
+	Hs
		648473 CALL3_HUMAN (8-83): 6.82e-14: 66.8: 38.16		IQGA1_HUMAN (1-1657): 0: 1732: 100.00
+	Hs
		483913 CALM1_HUMAN (54-159): 4.75e-09: 53.7: 24.30		IQGA1_HUMAN (1-1657): 0: 1732: 100.00
+	Hs
		483984 CALM2_HUMAN (54-159): 4.75e-09: 53.7: 24.30		IQGA1_HUMAN (1-1657): 0: 1732: 100.00
+	Hs
		484079 CALM3_HUMAN (54-159): 4.75e-09: 53.7: 24.30		IQGA1_HUMAN (1-1657): 0: 1732: 100.00
+	Hs
		57913 B4DJ51_HUMAN (54-159): 4.75e-09: 53.7: 24.30		A2RRC9_HUMAN (13-1657): 0: 1566: 58.93
+	Hs
		483946 CALM1_HUMAN (54-159): 4.75e-09: 53.7: 24.30		IQGA3_HUMAN (13-1657): 0: 1561: 58.87
+	Hs
		484020 CALM2_HUMAN (54-159): 4.75e-09: 53.7: 24.30		IQGA3_HUMAN (13-1657): 0: 1561: 58.87
+	Hs
		484161 CALM3_HUMAN (54-159): 4.75e-09: 53.7: 24.30		IQGA3_HUMAN (13-1657): 0: 1561: 58.87
+	Hs
		648499 CALL3_HUMAN (8-83): 6.82e-14: 66.8: 38.16		IQGA2_HUMAN (254-1657): 0: 1321: 54.09
+	Hs
		483957 CALM1_HUMAN (54-159): 4.75e-09: 53.7: 24.30		SYGP1_HUMAN (635-1477): 1.49e-108: 380: 12.26
+	Sc
		420355 CALM_YEAST (10-156): 5.03e-28: 103: 42.18		IQG1_YEAST (41-188): 1.08e-28: 128: 32.90
+	Sp
		144978 CALM_SCHPO (54-159): 4.18e-09: 54.1: 20.56		IQG1_SCHPO (11-204): 6.98e-41: 167: 38.14