Protein: PPIA
Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) (SP18) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed]

Gene: PPIA
Organism: Mus musculus
Interactions: 35
UniProt ID: P17742

Gene Ontology (top 5):
GO:0000413 - protein peptidyl-prolyl isomerization
GO:0001933 - negative regulation of protein phosphorylation
GO:0001934 - positive regulation of protein phosphorylation
GO:0003755 - peptidyl-prolyl cis-trans isomerase activity
GO:0005178 - integrin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

607831

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

3

4

High-throughput

0.656

High

607835

DLG4
Disks large homolog 4

3

2

High-throughput

0.656

High

607850

RHEB
GTP-binding protein Rheb

1

1

High-throughput

0.618

High

607855

HOME1
Homer protein homolog 1

1

5

High-throughput

0.536

High

607827

KCMA1
Calcium-activated potassium channel subunit alpha-1

1

4

High-throughput

0.489

High

607854

MBD2
Methyl-CpG-binding domain protein 2

1

0

Small-scale

0.480

High

148645

HDAC1
Histone deacetylase 1

1

7

Small-scale

0.479

High

398078

CFAD
Complement factor D

1

2

High-throughput

0.479

High

607828

STING
Stimulator of interferon genes protein

1

3

High-throughput

0.479

High

607829

CDKL5
Cyclin-dependent kinase-like 5

1

6

High-throughput

0.479

High

607830

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

5

High-throughput

0.479

High

607832

SC6A4
Sodium-dependent serotonin transporter

1

2

High-throughput

0.479

High

607836

TFE3
Transcription factor E3

1

5

High-throughput

0.479

High

607837

RIGI
Antiviral innate immune response receptor RIG-I

1

10

Small-scale

0.479

High

607839

ERBIN
Erbin

1

1

High-throughput

0.479

High

607840

WDTC1
WD and tetratricopeptide repeats protein 1

1

7

High-throughput

0.479

High

607843

A16L1
Autophagy-related protein 16-1

1

11

High-throughput

0.479

High

607844

CNOT3
CCR4-NOT transcription complex subunit 3

1

1

High-throughput

0.479

High

607846

FNDC5
Fibronectin type III domain-containing protein 5

1

2

High-throughput

0.479

High

607847

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

8

High-throughput

0.479

High

607849

EED
Polycomb protein EED

1

9

High-throughput

0.479

High

607853

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

2

Small-scale

0.479

High

467745

SODC
Superoxide dismutase [Cu-Zn]

1

4

High-throughput

0.445

High

607833

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

3

High-throughput

0.445

High

607841

ANS1B
Ankyrin repeat and sterile alpha motif domain-containing protein 1B

1

5

High-throughput

0.445

High

607845

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

2

High-throughput

0.445

High

607852

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

3

High-throughput

0.445

High

104458

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

2

High-throughput

0.437

High

312249

DHCR7
7-dehydrocholesterol reductase

1

1

High-throughput

0.437

High

607848

MAVS
Mitochondrial antiviral-signaling protein

1

3

Small-scale

0.437

High

607851

CNTP2
Contactin-associated protein-like 2

1

2

High-throughput

0.437

High

148223

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

1

High-throughput

0.407

High

607834

SOAT1
Sterol O-acyltransferase 1

1

2

High-throughput

0.407

High

607842

COX15
Heme A synthase COX15

1

1

High-throughput

0.407

High

607838

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025