Interactor 1: APOE (P02649)
Apolipoprotein E (Apo-E)
Gene: APOE

Interactor 2: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 0.60 0.691

The method score is based on:

Property Details
Experiments 28887769, 31270237, 26921451
Identification Methods affinity chromatography technology, pull down, enzyme linked immunosorbent assay, anti bait coimmunoprecipitation, molecular sieving, aggregation assay, solid phase assay
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005543 - phospholipid binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 7 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 317
Hs

1 140
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024