HitPredict

Interactor 1: CO9 (P02748)
Complement component C9 [Cleaved into: Complement component C9a; Complement component C9b]
Gene: C9

Interactor 2: CLUS (P10909)
Clusterin (Aging-associated gene 4 protein) (Apolipoprotein J) (Apo-J) (Complement cytolysis inhibitor) (CLI) (Complement-associated protein SP-40,40) (Ku70-binding protein 1) (NA1/NA2) (Sulfated glycoprotein 2) (SGP-2) (Testosterone-repressed prostate message 2) (TRPM-2) [Cleaved into: Clusterin beta chain (ApoJalpha) (Complement cytolysis inhibitor a chain) (SP-40,40 beta-chain); Clusterin alpha chain (ApoJbeta) (Complement cytolysis inhibitor b chain) (SP-40,40 alpha-chain)]
Gene: CLU

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	8345200
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0006956 - complement activation GO:0006958 - complement activation, classical pathway GO:0070062 - extracellular exosome and 1 others more... GO:0072562 - blood microparticle
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 559 Hs			1 449
+	Hs
		427756 CO8B_HUMAN (30-547): 2.81e-129: 391: 27.69		CLUS_HUMAN (1-449): 0: 697: 100.00
+	Hs
		498186 CO7_HUMAN (35-540): 3.69e-101: 326: 27.84		CLUS_HUMAN (1-449): 0: 697: 100.00
+	Hs
		500768 LRP2_HUMAN (54-258): 2.41e-29: 126: 9.95		CLUS_HUMAN (1-449): 0: 697: 100.00
+	Mm
		69880 B1AXJ3_MOUSE (178-272): 2.14e-12: 72.2: 8.25		CLUS_MOUSE (15-449): 0: 694: 76.78
+	Hs
		500904 LRP1B_HUMAN (135-277): 4.11e-11: 68.3: 10.27		CLUS_HUMAN (1-449): 0: 697: 100.00
+	Hs
		500721 TENA_HUMAN (4-140): 8.97e-11: 67.2: 15.94		CLUS_HUMAN (1-449): 0: 697: 100.00
+	Hs
		500781 LRP1_HUMAN (134-259): 1.14e-10: 66.8: 6.62		CLUS_HUMAN (1-449): 0: 697: 100.00