Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: DRD2 (P14416)
D(2) dopamine receptor (Dopamine D2 receptor)
Gene: DRD2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 28065597
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000139 - Golgi membrane
GO:0005886 - plasma membrane
GO:0005929 - cilium
GO:0043491 - phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO:0045944 - positive regulation of transcription by RNA polymerase II
and 2 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1210
Hs

1 443
+ Hs
+ Rn
+ Mm
+ Hs
+ Rn

Service provided by Combinatics, Japan

Last updated: 11Aug2025