Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: CCN2 (P29279)
CCN family member 2 (Cellular communication network factor 2) (Connective tissue growth factor) (Hypertrophic chondrocyte-specific protein 24) (Insulin-like growth factor-binding protein 8) (IBP-8) (IGF-binding protein 8) (IGFBP-8)
Gene: CCN2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 23175185
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001503 - ossification
GO:0005615 - extracellular space
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1210
Hs

1 349
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025