Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR
Interactor 2: HMGA2 (P52926)
High mobility group protein HMGI-C (High mobility group AT-hook protein 2)
Gene: HMGA2
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 0.60 | 0.500 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 35384245 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0019899 - enzyme binding GO:0043066 - negative regulation of apoptotic process GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0048146 - positive regulation of fibroblast proliferation |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
