HitPredict

Interactor 1: TFR1 (P02786)
Transferrin receptor protein 1 (TR) (TfR) (TfR1) (Trfr) (T9) (p90) (CD antigen CD71) [Cleaved into: Transferrin receptor protein 1, serum form (sTfR)]
Gene: TFRC

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005769 - early endosome GO:0005886 - plasma membrane GO:0010008 - endosome membrane GO:0019901 - protein kinase binding GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 760 Hs			1 196
+	Hs
		364237 TFR1_HUMAN (1-760): 0: 971: 100.00		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		364228 TFR1_HUMAN (1-760): 0: 971: 100.00		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		364158 TFR1_HUMAN (1-760): 0: 971: 100.00		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		364142 TFR1_HUMAN (1-760): 0: 971: 100.00		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		364244 TFR1_HUMAN (1-760): 0: 971: 100.00		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		364222 TFR1_HUMAN (1-760): 0: 971: 100.00		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		364223 TFR1_HUMAN (1-760): 0: 971: 100.00		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		364164 TFR1_HUMAN (1-760): 0: 971: 100.00		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		120270 TFR1_HUMAN (1-760): 0: 971: 100.00		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98