Protein: ACON2
Homocitrate dehydratase, mitochondrial (EC 4.2.1.-) (Aconitase 2)

Gene: ACON2, ACO2
Organism: Saccharomyces cerevisiae S288C
Interactions: 22
UniProt ID: P39533

Gene Ontology (top 5):
GO:0003994 - aconitate hydratase activity
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006099 - tricarboxylic acid cycle
GO:0019878 - lysine biosynthetic process via aminoadipic acid

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

812835

ACON2
Homocitrate dehydratase, mitochondrial

1

8

High-throughput

0.618

High

746257

NFU1
NifU-like protein, mitochondrial

2

4

Small-scale

0.584

High

792607

RM16
Large ribosomal subunit protein uL16m

1

0

High-throughput

0.493

High

510502

HSP77
Import motor subunit, mitochondrial

1

11

High-throughput

0.479

High

670724

SIS1
Protein SIS1

1

3

High-throughput

0.479

High

812836

BOL3
BolA-like protein 3

1

2

Small-scale

0.479

High

812841

SCC2
Sister chromatid cohesion protein 2

1

2

High-throughput

0.479

High

812842

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

1

High-throughput

0.479

High

602462

PHO85
Cyclin-dependent protein kinase PHO85

1

1

High-throughput

0.457

High

439137

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

1

High-throughput

0.445

High

526726

HSP72
Heat shock protein SSA2

1

10

High-throughput

0.445

High

544918

SSB1
Ribosome-associated molecular chaperone SSB1

1

11

High-throughput

0.445

High

626748

HSP60
Heat shock protein 60, mitochondrial

1

4

High-throughput

0.445

High

812837

SSB2
Ribosome-associated molecular chaperone SSB2

1

11

High-throughput

0.445

High

558729

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.437

High

707135

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

812838

SSN8
RNA polymerase II holoenzyme cyclin-like subunit

1

3

High-throughput

0.437

High

812840

RUVB1
RuvB-like protein 1

1

4

High-throughput

0.437

High

812844

RRP6
Exosome complex exonuclease RRP6

1

1

High-throughput

0.437

High

812843

RBX1
RING-box protein HRT1

2

0

High-throughput

0.307

High

812839

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025