Interactor 1: TFR1 (P02786)
Transferrin receptor protein 1 (TR) (TfR) (TfR1) (Trfr) (T9) (p90) (CD antigen CD71) [Cleaved into: Transferrin receptor protein 1, serum form (sTfR)]
Gene: TFRC

Interactor 2: NEMO (Q9Y6K9)
NF-kappa-B essential modulator (NEMO) (FIP-3) (IkB kinase-associated protein 1) (IKKAP1) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (I-kappa-B kinase subunit gamma) (IKK-gamma) (IKKG) (IkB kinase subunit gamma) (NF-kappa-B essential modifier)
Gene: IKBKG

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 23016877
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0042803 - protein homodimerization activity
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:0051092 - positive regulation of NF-kappaB transcription factor activity
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 760
Hs

1 419
+ Hs
+ Hs

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Last updated: 15 Jul 2024