Protein: CENPU
Inner kinetochore subunit AME1 (Associated with microtubules and essential protein 1) (CENP-U homolog) (Constitutive centromere-associated network protein AME1)

Gene: CENPU, AME1
Organism: Saccharomyces cerevisiae S288C
Interactions: 73
UniProt ID: P38313

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0000817 - COMA complex
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005816 - spindle pole body

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

797874

CENPN
Inner kinetochore subunit CHL4

6

0

Small-scale

0.892

High

797908

NKP2
Inner kinetochore subunit NKP2

5

0

Small-scale

0.866

High

779216

CENPA
Histone H3-like centromeric protein CSE4

12

1

Small-scale

0.756

High

797909

CENPO
Inner kinetochore subunit MCM21

9

1

Small-scale

0.750

High

797898

CENPQ
Inner kinetochore subunit OKP1

16

0

Small-scale

0.731

High

797885

DSN1
Kinetochore-associated protein DSN1

15

0

Small-scale

0.727

High

797890

NNF1
Kinetochore-associated protein NNF1

10

0

Small-scale

0.722

High

797904

CENPP
Inner kinetochore subunit CTF19

10

0

Small-scale

0.721

High

797877

MTW1
Kinetochore-associated protein MTW1

9

0

Small-scale

0.719

High

797910

NSL1
Kinetochore-associated protein NSL1

8

0

Small-scale

0.714

High

797103

CENPL
Inner kinetochore subunit IML3

8

0

Small-scale

0.711

High

797912

CENPH
Inner kinetochore subunit MCM16

6

0

Small-scale

0.696

High

797914

NKP1
Inner kinetochore subunit NKP1

5

0

Small-scale

0.672

High

797915

CENPI
Inner kinetochore subunit CTF3

5

0

Small-scale

0.669

High

382065

H4
Histone H4

4

0

Small-scale

0.648

High

797891

CENPK
Inner kinetochore subunit MCM22

3

0

Small-scale

0.622

High

755232

NUF2
Kinetochore protein NUF2

3

0

Small-scale

0.622

High

797895

KNL1
Outer kinetochore KNL1 complex subunit SPC105

3

0

Small-scale

0.614

High

381503

H2B2
Histone H2B.2

3

0

Small-scale

0.613

High

419418

H2A1
Histone H2A.1

3

0

Small-scale

0.613

High

763737

CENPC
Inner kinetochore subunit MIF2

3

0

Small-scale

0.613

High

797888

CENPT
Inner kinetochore subunit CNN1

3

0

Small-scale

0.606

High

750829

PRS6B
26S proteasome regulatory subunit 6B homolog

2

0

Small-scale

0.594

High

797901

H3
Histone H3

2

1

Small-scale

0.584

High

797902

HSK3
DASH complex subunit HSK3

2

0

High-throughput

0.576

High

797878

LIS1
Nuclear distribution protein PAC1

2

0

High-throughput

0.570

High

738745

CBF3A
Centromere DNA-binding protein complex CBF3 subunit A

2

0

Small-scale

0.559

High

797873

CENPU
Inner kinetochore subunit AME1

2

0

Small-scale

0.559

High

797884

NDC80
Kinetochore protein NDC80

2

0

Small-scale

0.559

High

797906

ZWINT
Outer kinetochore KNL1 complex subunit KRE28

2

0

Small-scale

0.559

High

797907

SPC24
Kinetochore protein SPC24

2

0

Small-scale

0.559

High

797911

PSH1
RING finger protein PSH1

2

0

Small-scale

0.559

High

797882

SSB2
Ribosome-associated molecular chaperone SSB2

2

1

High-throughput

0.552

High

797900

MPS1
Serine/threonine-protein kinase MPS1

1

1

High-throughput

0.536

High

364499

CDK1
Cyclin-dependent kinase 1

1

1

Small-scale

0.501

High

602431

PHO85
Cyclin-dependent protein kinase PHO85

1

1

Small-scale

0.501

High

667029

PCL1
PHO85 cyclin-1

1

0

Small-scale

0.480

High

797331

INCE
Inner centromere protein SLI15

1

0

Small-scale

0.480

High

438293

NOT3
General negative regulator of transcription subunit 3

1

0

High-throughput

0.460

High

626498

AP1
AP-1-like transcription factor YAP1

1

0

High-throughput

0.460

High

646030

KIN3
Serine/threonine-protein kinase KIN3

1

0

High-throughput

0.460

High

797876

END3
Actin cytoskeleton-regulatory complex protein END3

1

0

High-throughput

0.460

High

797879

VAB2
Biogenesis of lysosome-related organelles complex 1 subunit VAB2

1

0

High-throughput

0.460

High

797883

MED3
Mediator of RNA polymerase II transcription subunit 3

1

0

High-throughput

0.460

High

797889

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

0

High-throughput

0.460

High

797894

NBP1
NAP1-binding protein

1

0

High-throughput

0.460

High

797899

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.460

High

797903

PRS8
26S proteasome regulatory subunit 8 homolog

1

0

High-throughput

0.460

High

706942

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

712977

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

763775

CBF3C
Centromere DNA-binding protein complex CBF3 subunit C

1

0

Small-scale

0.458

High

797875

AURK
Aurora kinase

1

0

Small-scale

0.458

High

797880

SPC25
Kinetochore protein SPC25

1

0

Small-scale

0.458

High

797886

CBF3B
Centromere DNA-binding protein complex CBF3 subunit B

1

0

Small-scale

0.458

High

797892

SKP1
Suppressor of kinetochore protein 1

1

0

Small-scale

0.458

High

797896

YBP2
YAP1-binding protein 2

1

0

Small-scale

0.458

High

797897

DAM1
DASH complex subunit DAM1

1

0

High-throughput

0.458

High

797905

SPC19
DASH complex subunit SPC19

1

0

High-throughput

0.458

High

797913

SCM3
Protein SCM3

1

0

Small-scale

0.458

High

797916

CENPW
Inner kinetochore subunit WIP1

1

0

Small-scale

0.458

High

523773

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

526544

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

544674

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

741473

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

726978

HS104
Heat shock protein 104

1

0

High-throughput

0.426

High

797893

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

550652

SIR4
Regulatory protein SIR4

1

0

High-throughput

0.251

Low

736964

CDC3
Cell division control protein 3

1

0

High-throughput

0.251

Low

797881

TSC11
Target of rapamycin complex 2 subunit TSC11

1

0

High-throughput

0.251

Low

797887

BNI1
Protein BNI1

1

0

High-throughput

0.249

Low

797917

CENPX
Inner kinetochore subunit MHF2

1

0

Small-scale

0.249

Low

797918

CENPS
Inner kinetochore subunit MHF1

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025