HitPredict

Interactor 1: PGK1 (P00558)
Phosphoglycerate kinase 1 (EC 2.7.11.1) (EC 2.7.2.3) (Cell migration-inducing gene 10 protein) (Primer recognition protein 2) (PRP 2)
Gene: PGK1

Interactor 2: PGK2 (P07205)
Phosphoglycerate kinase 2 (EC 2.7.2.3) (Phosphoglycerate kinase, testis specific)
Gene: PGK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 28514442, 33961781, 38334954, 35271311, 34349018, 35235311, 35575683, 39358380, 31839598
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PGK~PGK
Common GO terms GO:0004618 - phosphoglycerate kinase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006094 - gluconeogenesis
GO:0006096 - glycolytic process
and 4 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 417
Hs

1 417
+ Hs
+ Sc
+ Cj
+ Ec

Service provided by Combinatics, Japan

Last updated: 11Aug2025