HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: ECM29 (P38737)
Proteasome component ECM29 (Extracellular mutant protein 29)
Gene: ECM29

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	31399574, 21321079, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0043248 - proteasome assembly
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 709 Sc			1 1868
+	Sc
		543679 HSC82_YEAST (1-709): 0: 973: 94.64		ECM29_YEAST (1-1868): 0: 1493: 100.00
+	Mm
		432420 HS90A_MOUSE (4-709): 0: 1012: 60.72		IMB1_MOUSE (808-1650): 2.68e-117: 395: 10.62
+	Sc
		366915 HSP82_YEAST (1-709): 0: 984: 100.00		IMB1_YEAST (809-1639): 3.25e-83: 295: 11.54
+	Sc
		366065 HSP82_YEAST (1-709): 0: 984: 100.00		GCN1_YEAST (4-1465): 4.1e-76: 284: 12.81
+	Sc
		544439 HSC82_YEAST (1-709): 0: 973: 94.64		IMB1_YEAST (809-1639): 3.25e-83: 295: 11.54
+	Sc
		543486 HSC82_YEAST (1-709): 0: 973: 94.64		GCN1_YEAST (4-1465): 4.1e-76: 284: 12.81
+	Hs
		438325 HS90B_HUMAN (5-709): 0: 1026: 62.13		CAND1_HUMAN (1380-1695): 2.42e-09: 64.7: 13.23
+	Hs
		432021 HS90A_HUMAN (4-709): 0: 1015: 60.83		CAND1_HUMAN (1380-1695): 2.42e-09: 64.7: 13.23
+	Hs
		538300 ENPL_HUMAN (3-684): 0: 904: 45.97		CAND1_HUMAN (1380-1695): 2.42e-09: 64.7: 13.23