HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: GLRX3 (Q03835)
Monothiol glutaredoxin-3
Gene: GRX3

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31399574
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 709 Sc			1 250
+	Sc
		544345 HSC82_YEAST (1-709): 0: 973: 94.64		GLRX3_YEAST (1-250): 8.59e-73: 224: 100.00
+	Sc
		366014 HSP82_YEAST (1-709): 0: 984: 100.00		GLRX4_YEAST (1-249): 5.5e-66: 206: 66.27
+	Sc
		543421 HSC82_YEAST (1-709): 0: 973: 94.64		GLRX4_YEAST (1-249): 5.5e-66: 206: 66.27
+	Hs
		431462 HS90A_HUMAN (4-709): 0: 1015: 60.83		THIO_HUMAN (3-109): 2.43e-35: 123: 31.78
+	Sc
		366767 HSP82_YEAST (1-709): 0: 984: 100.00		GLRX5_YEAST (148-247): 1.85e-35: 125: 43.81
+	Sc
		365815 HSP82_YEAST (1-709): 0: 984: 100.00		TRX2_YEAST (3-106): 2.6e-35: 123: 25.96
+	Sc
		365806 HSP82_YEAST (1-709): 0: 984: 100.00		TRX1_YEAST (3-106): 5.49e-35: 122: 25.00
+	Sc
		544280 HSC82_YEAST (1-709): 0: 973: 94.64		GLRX5_YEAST (148-247): 1.85e-35: 125: 43.81
+	Sc
		543221 HSC82_YEAST (1-709): 0: 973: 94.64		TRX2_YEAST (3-106): 2.6e-35: 123: 25.96
+	Sc
		543214 HSC82_YEAST (1-709): 0: 973: 94.64		TRX1_YEAST (3-106): 5.49e-35: 122: 25.00
+	Hs
		538242 ENPL_HUMAN (3-684): 0: 904: 45.97		PDIA6_HUMAN (3-245): 2.57e-45: 158: 13.96
+	Hs
		538119 ENPL_HUMAN (3-684): 0: 904: 45.97		PDIA3_HUMAN (4-121): 4.45e-24: 102: 13.45
+	Hs
		531703 ENPL_HUMAN (3-684): 0: 904: 45.97		PDIA4_HUMAN (4-118): 3.48e-22: 96.9: 13.33
+	Rn
		751963 ENPL_RAT (3-704): 0: 908: 45.10		PDIA4_RAT (2-118): 2.2e-20: 91.9: 13.12
+	Zm
		35515 A0A1D6LMW9_MAIZE (2-684): 0: 840: 47.40		K7UQQ8_MAIZE (115-238): 2.8e-37: 130: 30.65
+	Dm
		870455 Q9VAY2_DROME (3-680): 0: 837: 46.67		PDI_DROME (4-114): 3.54e-21: 93.8: 14.04