HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: RSC2 (Q06488)
Chromatin structure-remodeling complex subunit RSC2 (RSC complex subunit RSC2) (Remodel the structure of chromatin complex subunit 2)
Gene: RSC2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	19536198
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 709 Sc			1 889
+	Hs
		243816 HS90B_HUMAN (5-709): 0: 1026: 62.13		BRD4_HUMAN (2-329): 9.37e-27: 120: 12.65
+	Hs
		243814 HS90A_HUMAN (4-709): 0: 1015: 60.83		BRD4_HUMAN (2-329): 9.37e-27: 120: 12.65
+	Hs
		432282 HS90A_HUMAN (4-709): 0: 1015: 60.83		BRD7_HUMAN (2-258): 1.02e-24: 112: 12.36
+	Rn
		948938 HS90A_RAT (4-709): 0: 1014: 60.72		Q6AYL3_RAT (1-69): 4.49e-10: 64: 19.72
+	Sc
		366084 HSP82_YEAST (1-709): 0: 984: 100.00		SPT7_YEAST (158-404): 1.37e-18: 93.5: 11.86
+	Sc
		543505 HSC82_YEAST (1-709): 0: 973: 94.64		SPT7_YEAST (158-404): 1.37e-18: 93.5: 11.86
+	Sc
		366003 HSP82_YEAST (1-709): 0: 984: 100.00		STH1_YEAST (275-377): 2.49e-11: 69.8: 24.27
+	Sc
		366757 HSP82_YEAST (1-709): 0: 984: 100.00		RSC4_YEAST (34-128): 1.91e-10: 66.7: 27.84
+	Sc
		544136 HSC82_YEAST (1-709): 0: 973: 94.64		RSC1_YEAST (4-149): 1.8e-12: 73.6: 18.24
+	Sc
		544268 HSC82_YEAST (1-709): 0: 973: 94.64		RSC4_YEAST (34-128): 1.91e-10: 66.7: 27.84
+	Hs
		538160 ENPL_HUMAN (3-684): 0: 904: 45.97		SMCA4_HUMAN (9-122): 8.4e-29: 126: 29.92
+	Hs
		243866 ENPL_HUMAN (3-684): 0: 904: 45.97		BRD4_HUMAN (2-329): 9.37e-27: 120: 12.65
+	Hs
		170238 ENPL_HUMAN (3-684): 0: 904: 45.97		TIF1A_HUMAN (47-132): 1.21e-11: 71: 32.22