HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: HOSM (Q12122)
Homocitrate synthase, mitochondrial (HCS) (EC 2.3.3.14)
Gene: LYS21

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	15879519, 31399574
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 709 Sc			1 440
+	Sc
		544578 HSC82_YEAST (1-709): 0: 973: 94.64		HOSM_YEAST (1-440): 1.34e-175: 500: 100.00
+	Sc
		366565 HSP82_YEAST (1-709): 0: 984: 100.00		HOSC_YEAST (21-437): 1.74e-160: 461: 92.36
+	Sc
		544058 HSC82_YEAST (1-709): 0: 973: 94.64		HOSC_YEAST (21-437): 1.74e-160: 461: 92.36
+	Ca
		804488 HSP90_CANAL (4-709): 0: 959: 81.75		Q59TC4_CANAL (20-432): 1.07e-159: 458: 87.50
+	Sc
		365552 HSP82_YEAST (1-709): 0: 984: 100.00		LEU1_YEAST (11-435): 1.17e-119: 363: 16.25
+	Sc
		411210 HSC82_YEAST (1-709): 0: 973: 94.64		LEU1_YEAST (11-435): 1.17e-119: 363: 16.25
+	Sc
		365956 HSP82_YEAST (1-709): 0: 984: 100.00		PYC2_YEAST (9-405): 1.1e-104: 337: 17.29
+	Sc
		543369 HSC82_YEAST (1-709): 0: 973: 94.64		PYC2_YEAST (9-405): 1.1e-104: 337: 17.29