Protein: SA185
SIT4-associating protein SAP185

Gene: SA185, SAP185
Organism: Saccharomyces cerevisiae S288C
Interactions: 138
UniProt ID: P40856

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0002098 - tRNA wobble uridine modification
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

633478

PP11
Serine/threonine-protein phosphatase PP1-1

10

8

Small-scale

0.756

High

828498

RTS3
Protein phosphatase type 2A regulatory subunit RTS3

3

1

High-throughput

0.671

High

828521

TIP41
Type 2A phosphatase activator TIP41

3

3

High-throughput

0.657

High

622968

CSK22
Casein kinase II subunit alpha'

2

8

High-throughput

0.628

High

709404

HRR25
Casein kinase I homolog HRR25

2

3

High-throughput

0.628

High

805187

TRA1
SAGA complex/NuA4 acetyltransferase complex subunit TRA1

2

5

High-throughput

0.628

High

806295

KOG1
Target of rapamycin complex 1 subunit KOG1

2

1

High-throughput

0.614

High

815819

BEM2
GTPase-activating protein BEM2/IPL2

2

0

High-throughput

0.602

High

828487

EPL1
Enhancer of polycomb-like protein 1

2

0

High-throughput

0.602

High

828512

EAF1
Chromatin modification-related protein EAF1

2

0

High-throughput

0.602

High

828494

MDS3
Negative regulator of sporulation MDS3

2

1

High-throughput

0.601

High

828482

SA185
SIT4-associating protein SAP185

2

4

High-throughput

0.588

High

367051

ATPB
ATP synthase subunit beta, mitochondrial

2

4

High-throughput

0.584

High

486214

TBA1
Tubulin alpha-1 chain

2

1

High-throughput

0.584

High

742870

HSP79
Heat shock protein homolog SSE2

2

12

High-throughput

0.584

High

416888

CDC25
Cell division control protein 25

2

0

High-throughput

0.576

High

545201

SSB1
Ribosome-associated molecular chaperone SSB1

2

7

High-throughput

0.571

High

579561

HSC82
ATP-dependent molecular chaperone HSC82

2

1

High-throughput

0.571

High

713272

MCM5
Minichromosome maintenance protein 5

2

0

High-throughput

0.547

High

394050

EFTU
Elongation factor Tu, mitochondrial

1

2

High-throughput

0.536

High

645939

DBF2
Cell cycle protein kinase DBF2

1

2

High-throughput

0.536

High

646052

KIN3
Serine/threonine-protein kinase KIN3

1

6

High-throughput

0.536

High

722015

XPO1
Exportin-1

1

12

High-throughput

0.536

High

756606

MKS1
Negative regulator of RAS-cAMP pathway

1

1

High-throughput

0.536

High

762831

TOR1
Serine/threonine-protein kinase TOR1

1

5

High-throughput

0.536

High

763335

TAF14
Transcription initiation factor TFIID subunit 14

1

1

High-throughput

0.536

High

828483

LST8
Target of rapamycin complex subunit LST8

1

1

High-throughput

0.536

High

828484

SMK1
Sporulation-specific mitogen-activated protein kinase SMK1

1

1

High-throughput

0.536

High

828493

MRK1
Serine/threonine-protein kinase MRK1

1

8

High-throughput

0.536

High

828495

SGF73
SAGA complex subunit SGF73

1

1

High-throughput

0.536

High

828500

AF9
Protein AF-9 homolog

1

1

High-throughput

0.536

High

828502

ARP4
Actin-related protein 4

1

1

High-throughput

0.536

High

828503

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

1

1

High-throughput

0.536

High

828506

DIG1
Down-regulator of invasive growth 1

1

1

High-throughput

0.536

High

828507

GCN5
Histone acetyltransferase GCN5

1

2

High-throughput

0.536

High

664308

SSD1
Protein SSD1

1

1

High-throughput

0.515

High

828505

XRN2
5'-3' exoribonuclease 2

1

1

High-throughput

0.515

High

417123

VDAC1
Non-selective voltage-gated ion channel 1

1

0

High-throughput

0.513

High

453963

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.513

High

642147

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

High-throughput

0.513

High

678838

AHC2
ADA histone acetyltransferase complex component 2

1

0

High-throughput

0.513

High

803228

PHS
Putative pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.513

High

825959

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.513

High

828490

SSN8
RNA polymerase II holoenzyme cyclin-like subunit

1

0

High-throughput

0.513

High

828492

TAF4
Transcription initiation factor TFIID subunit 4

1

0

High-throughput

0.513

High

828515

ESA1
Histone acetyltransferase ESA1

1

0

High-throughput

0.513

High

828520

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.513

High

509593

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

3

High-throughput

0.501

High

602509

PHO85
Cyclin-dependent protein kinase PHO85

1

1

Small-scale

0.501

High

359024

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

3

High-throughput

0.500

High

359488

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

3

High-throughput

0.500

High

367766

ENO1
Enolase 1

1

1

High-throughput

0.500

High

405102

LEU3
3-isopropylmalate dehydrogenase

1

1

High-throughput

0.500

High

452920

ATPA
ATP synthase subunit alpha, mitochondrial

1

4

High-throughput

0.500

High

590650

HSP26
Heat shock protein 26

1

1

High-throughput

0.500

High

597168

BIP
Endoplasmic reticulum chaperone BiP

1

2

High-throughput

0.500

High

760280

BMH2
Protein BMH2

1

1

High-throughput

0.500

High

801849

KSP1
Serine/threonine-protein kinase KSP1

1

4

High-throughput

0.500

High

366816

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.493

High

444548

DED1
ATP-dependent RNA helicase DED1

1

0

High-throughput

0.493

High

828497

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

High-throughput

0.493

High

828523

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.493

High

597485

EF3A
Elongation factor 3A

1

2

High-throughput

0.489

High

678109

SYP1
Suppressor of yeast profilin deletion

1

1

High-throughput

0.489

High

734315

DBF20
Serine/threonine-protein kinase DBF20

1

2

High-throughput

0.489

High

739510

DUR1
Urea amidolyase [Includes: Urea carboxylase

1

1

High-throughput

0.489

High

793163

AKL1
Serine/threonine-protein kinase AKL1

1

3

High-throughput

0.489

High

828516

HRK1
Serine/threonine-protein kinase HRK1

1

1

High-throughput

0.489

High

828517

TCO89
Target of rapamycin complex 1 subunit TCO89

1

1

High-throughput

0.489

High

364585

CDK1
Cyclin-dependent kinase 1

1

1

Small-scale

0.481

High

667035

PCL1
PHO85 cyclin-1

1

0

Small-scale

0.480

High

452515

PUR2
Bifunctional purine biosynthetic protein ADE5,7 [Includes: Phosphoribosylamine--glycine ligase

1

0

High-throughput

0.479

High

484771

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.479

High

661644

MPCP
Mitochondrial phosphate carrier protein

1

0

High-throughput

0.479

High

815729

SAHH
Adenosylhomocysteinase

1

0

High-throughput

0.479

High

828501

ACT
Actin

1

0

High-throughput

0.479

High

430867

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

3

Small-scale

0.479

High

707345

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

817725

TSC11
Target of rapamycin complex 2 subunit TSC11

1

0

High-throughput

0.460

High

828519

SAS10
Something about silencing protein 10

1

0

High-throughput

0.460

High

360993

CCPR
Cytochrome c peroxidase, mitochondrial

1

0

High-throughput

0.458

High

435151

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

576069

AROF
Phospho-2-dehydro-3-deoxyheptonate aldolase, phenylalanine-inhibited

1

0

High-throughput

0.458

High

585501

KCY
Uridylate kinase

1

0

High-throughput

0.458

High

594415

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

Small-scale

0.458

High

627799

PYRC
Dihydroorotase

1

0

High-throughput

0.458

High

790260

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

0

High-throughput

0.458

High

792091

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.458

High

793610

ARA1
D-arabinose dehydrogenase [NAD(P)+] heavy chain

1

0

High-throughput

0.458

High

795402

ATG8
Autophagy-related protein 8

1

0

High-throughput

0.458

High

828510

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

802640

YHI0
Putative proline--tRNA ligase YHR020W

1

1

High-throughput

0.457

High

392876

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.445

High

394645

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

453644

PYR1
Multifunctional protein URA2

1

3

High-throughput

0.445

High

510565

HSP77
Import motor subunit, mitochondrial

1

4

High-throughput

0.445

High

524222

HSP71
Heat shock protein SSA1

1

7

High-throughput

0.445

High

526916

HSP72
Heat shock protein SSA2

1

7

High-throughput

0.445

High

626773

HSP60
Heat shock protein 60, mitochondrial

1

1

High-throughput

0.445

High

727100

HS104
Heat shock protein 104

1

1

High-throughput

0.445

High

741756

HSP7F
Heat shock protein homolog SSE1

1

12

High-throughput

0.445

High

744081

PMD1
Negative regulator of sporulation PMD1

1

1

High-throughput

0.445

High

752365

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

797921

SDS24
Protein SDS24

1

3

High-throughput

0.445

High

811327

CAJ1
Protein CAJ1

1

1

High-throughput

0.445

High

811462

XDJ1
DnaJ protein homolog XDJ1

1

3

High-throughput

0.445

High

816251

HSP7E
Heat shock protein SSC3, mitochondrial

1

4

High-throughput

0.445

High

818983

SSB2
Ribosome-associated molecular chaperone SSB2

1

7

High-throughput

0.445

High

828488

RMD8
Sporulation protein RMD8

1

1

High-throughput

0.445

High

828508

RMD1
Sporulation protein RMD1

1

1

High-throughput

0.445

High

828511

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

10

High-throughput

0.445

High

828513

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

2

High-throughput

0.445

High

753101

NIP80
Protein NIP100

1

2

High-throughput

0.439

High

762918

CYPD
Peptidyl-prolyl cis-trans isomerase D

1

1

High-throughput

0.437

High

828514

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.437

High

828518

AP3D
AP-3 complex subunit delta

1

9

High-throughput

0.437

High

828504

ADA2
SAGA complex subunit ADA2

1

0

High-throughput

0.426

High

365078

KPYK1
Pyruvate kinase 1

1

1

High-throughput

0.407

High

554007

TCPA
T-complex protein 1 subunit alpha

1

1

High-throughput

0.407

High

560717

KIN2
Serine/threonine-protein kinase KIN2

1

4

High-throughput

0.407

High

592306

VATB
V-type proton ATPase subunit B

1

4

High-throughput

0.407

High

671651

SCJ1
DnaJ-related protein SCJ1

1

1

High-throughput

0.407

High

823266

JEM1
DnaJ-like chaperone JEM1

1

2

High-throughput

0.407

High

828485

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.407

High

598359

ATE1
Arginyl-tRNA--protein transferase 1

1

0

High-throughput

0.279

Low

828509

YM59
Uncharacterized protein YMR209C

1

0

High-throughput

0.279

Low

746286

UGPA1
UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.261

Low

828496

NNF2
Protein NNF2

1

0

High-throughput

0.251

Low

828522

MPC70
Sporulation-specific protein 21

1

0

High-throughput

0.251

Low

793048

PDX3
Pyridoxamine 5'-phosphate oxidase

1

0

High-throughput

0.249

Low

828499

GIS2
Zinc finger protein GIS2

1

0

High-throughput

0.249

Low

386743

TBB
Tubulin beta chain

1

0

High-throughput

0.232

Low

796157

OLA1
Obg-like ATPase 1

1

0

High-throughput

0.232

Low

798038

YB75
Uncharacterized protein YBR225W

1

0

High-throughput

0.232

Low

828486

TCPH
T-complex protein 1 subunit eta

1

0

High-throughput

0.232

Low

828489

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low

828491

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025