HitPredict

Interactor 1: EF1A (P02994)
Elongation factor 1-alpha (EF-1-alpha) (Eukaryotic elongation factor 1A) (eEF1A) (Translation elongation factor 1A)
Gene: TEF1

Interactor 2: EF3A (P16521)
Elongation factor 3A (EF-3) (EF-3A) (EC 3.6.4.-) (Eukaryotic elongation factor 3) (eEF3) (Translation elongation factor 3A) (Yeast elongation factor 3)
Gene: YEF3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	9990316, 9705146, 22404850
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001933 - negative regulation of protein phosphorylation GO:0003746 - translation elongation factor activity GO:0005840 - ribosome GO:0006414 - translational elongation GO:0006469 - negative regulation of protein kinase activity
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 458 Sc			1 1044
+	Sc
		368480 EF1A_YEAST (1-443): 0: 538: 100.00		NEW1_YEAST (11-1039): 9.7e-141: 454: 33.40
+	Sc
		367919 EF1A_YEAST (1-443): 0: 538: 100.00		GCN1_YEAST (5-465): 9.92e-73: 267: 19.83
+	Hs
		706703 EF1A1_HUMAN (1-457): 0: 548: 80.44		MRP1_HUMAN (761-1006): 1.03e-29: 130: 14.23
+	Sc
		368097 EF1A_YEAST (1-443): 0: 538: 100.00		ARB1_YEAST (766-1041): 7.09e-31: 131: 14.95
+	Sc
		368167 EF1A_YEAST (1-443): 0: 538: 100.00		GCN20_YEAST (631-1027): 1.84e-27: 121: 19.21