Protein: HSP12
12 kDa heat shock protein (Glucose and lipid-regulated protein)

Gene: HSP12
Organism: Saccharomyces cerevisiae S288C
Interactions: 129
UniProt ID: P22943

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005768 - endosome
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

578873

HSC82
ATP-dependent molecular chaperone HSC82

2

1

High-throughput

0.584

High

394249

EF1A
Elongation factor 1-alpha

2

0

High-throughput

0.569

High

449070

CALM
Calmodulin

2

0

High-throughput

0.563

High

647695

RFA1
Replication factor A protein 1

2

0

High-throughput

0.563

High

653915

RRP6
Exosome complex exonuclease RRP6

2

0

High-throughput

0.559

High

575891

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.513

High

602110

SPO12
Sporulation-specific protein 12

1

0

High-throughput

0.513

High

653850

NNK1
Nitrogen network kinase 1

1

0

High-throughput

0.480

High

653871

BNI1
Protein BNI1

1

0

High-throughput

0.480

High

416372

HXKA
Hexokinase-1

1

0

High-throughput

0.479

High

367696

ENO1
Enolase 1

1

1

High-throughput

0.479

High

367898

ENO2
Enolase 2

1

1

High-throughput

0.479

High

392253

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.479

High

653834

HS104
Heat shock protein 104

1

1

High-throughput

0.479

High

653846

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.479

High

646300

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.458

High

653823

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

653827

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

653831

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

653835

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

653854

ATG8
Autophagy-related protein 8

1

0

High-throughput

0.458

High

653857

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.458

High

653861

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

653872

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.458

High

653874

SCD6
Protein SCD6

1

0

Small-scale

0.458

High

653880

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

653894

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

High-throughput

0.458

High

653902

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

653837

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

1

High-throughput

0.445

High

653839

HSP7F
Heat shock protein homolog SSE1

1

1

High-throughput

0.445

High

653840

STH1
Nuclear protein STH1/NPS1

1

1

High-throughput

0.445

High

653855

ECM29
Proteasome component ECM29

1

1

High-throughput

0.445

High

399298

PYRF
Orotidine 5'-phosphate decarboxylase

1

0

High-throughput

0.426

High

415200

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.426

High

419360

H2A1
Histone H2A.1

1

0

High-throughput

0.426

High

434517

RL22A
Large ribosomal subunit protein eL22A

1

0

High-throughput

0.426

High

444425

DED1
ATP-dependent RNA helicase DED1

1

0

High-throughput

0.426

High

448884

TYSY
Thymidylate synthase

1

0

High-throughput

0.426

High

454030

GCR1
Glycolytic genes transcriptional activator GCR1

1

0

High-throughput

0.426

High

454402

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.426

High

523096

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.426

High

543857

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

550569

SST2
Protein SST2

1

0

High-throughput

0.426

High

584344

GCN2
eIF-2-alpha kinase GCN2

1

0

High-throughput

0.426

High

584402

KGUA
Guanylate kinase

1

0

High-throughput

0.426

High

645223

GAS1
1,3-beta-glucanosyltransferase GAS1

1

0

High-throughput

0.426

High

653821

GYS1
Glycogen [starch] synthase isoform 1

1

0

High-throughput

0.426

High

653822

SNT1
Probable DNA-binding protein SNT1

1

0

High-throughput

0.426

High

653824

YC21A
Transposon Ty2-C Gag polyprotein

1

0

High-throughput

0.426

High

653825

SRO9
RNA-binding protein SRO9

1

0

High-throughput

0.426

High

653826

NOT1
General negative regulator of transcription subunit 1

1

0

High-throughput

0.426

High

653830

KIP1
Kinesin-like protein KIP1

1

0

High-throughput

0.426

High

653832

RIF1
Telomere length regulator protein RIF1

1

0

High-throughput

0.426

High

653841

PP12
Serine/threonine-protein phosphatase PP1-2

1

0

High-throughput

0.426

High

653842

RTG1
Retrograde regulation protein 1

1

0

High-throughput

0.426

High

653843

SMC1
Structural maintenance of chromosomes protein 1

1

0

High-throughput

0.426

High

653844

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.426

High

653845

PRP8
Pre-mRNA-splicing factor 8

1

0

High-throughput

0.426

High

653848

GCN1
eIF-2-alpha kinase activator GCN1

1

0

High-throughput

0.426

High

653849

UBX1
UBX domain-containing protein 1

1

0

High-throughput

0.426

High

653851

NOP4
Nucleolar protein 4

1

0

High-throughput

0.426

High

653852

AAP1
Alanine/arginine aminopeptidase

1

0

High-throughput

0.426

High

653853

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

0

High-throughput

0.426

High

653856

HRB1
Serine/arginine

1

0

High-throughput

0.426

High

653858

POP2
Poly(A) ribonuclease POP2

1

0

High-throughput

0.426

High

653859

STM1
Suppressor protein STM1

1

0

High-throughput

0.426

High

653860

CAJ1
Protein CAJ1

1

0

High-throughput

0.426

High

653863

PCL6
PHO85 cyclin-6

1

0

High-throughput

0.426

High

653864

TSC11
Target of rapamycin complex 2 subunit TSC11

1

0

High-throughput

0.426

High

653865

PP4R3
Serine/threonine-protein phosphatase 4 regulatory subunit 3

1

0

High-throughput

0.426

High

653866

RFC4
Replication factor C subunit 4

1

0

High-throughput

0.426

High

653867

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.426

High

653868

BMT5
25S rRNA

1

0

High-throughput

0.426

High

653869

CSN11
Cop9 signalosome complex subunit 11

1

0

High-throughput

0.426

High

653873

FIP1
Pre-mRNA polyadenylation factor FIP1

1

0

High-throughput

0.426

High

653876

IML1
Vacuolar membrane-associated protein IML1

1

0

High-throughput

0.426

High

653878

TRM9
tRNA

1

0

High-throughput

0.426

High

653879

SWC4
SWR1-complex protein 4

1

0

High-throughput

0.426

High

653882

RTS3
Protein phosphatase type 2A regulatory subunit RTS3

1

0

High-throughput

0.426

High

653884

ATG2
Autophagy-related protein 2

1

0

High-throughput

0.426

High

653885

APC1
Anaphase-promoting complex subunit 1

1

0

High-throughput

0.426

High

653888

IDHH
Isocitrate dehydrogenase [NADP]

1

0

High-throughput

0.426

High

653889

RL15B
Large ribosomal subunit protein eL15B

1

0

High-throughput

0.426

High

653890

CTR9
RNA polymerase-associated protein CTR9

1

0

High-throughput

0.426

High

653891

PRS8
26S proteasome regulatory subunit 8 homolog

1

0

High-throughput

0.426

High

653895

THADA
tRNA

1

0

High-throughput

0.426

High

653897

DOP1
Protein DOP1

1

0

High-throughput

0.426

High

653898

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.426

High

653899

YM04
Abasic site processing protein YMR114C

1

0

High-throughput

0.426

High

653901

CYK2
Cytokinesis protein 2

1

0

High-throughput

0.426

High

653904

EAF1
Chromatin modification-related protein EAF1

1

0

High-throughput

0.426

High

653906

MRL1
Mannose 6-phosphate receptor-like protein 1

1

0

High-throughput

0.426

High

653907

BRE1
E3 ubiquitin-protein ligase BRE1

1

0

High-throughput

0.426

High

653908

AVO1
Target of rapamycin complex 2 subunit AVO1

1

0

High-throughput

0.426

High

653909

RTC1
Restriction of telomere capping protein 1

1

0

High-throughput

0.426

High

653911

DIA2
Protein DIA2

1

0

High-throughput

0.426

High

653913

AEP3
ATPase expression protein 3

1

0

High-throughput

0.426

High

653916

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.426

High

653918

CRM2
Homeostatic regulator of DAG

1

0

High-throughput

0.426

High

653919

PST1
Cell wall mannoprotein PST1

1

0

High-throughput

0.426

High

653920

CEX1
Cytoplasmic export protein 1

1

0

High-throughput

0.426

High

653921

SFG1
Superficial pseudohyphal growth protein 1

1

0

High-throughput

0.426

High

653922

SEY1
Protein SEY1

1

0

High-throughput

0.426

High

653828

RFA2
Replication factor A protein 2

2

0

High-throughput

0.307

High

653900

SOV1
Protein SOV1, mitochondrial

1

0

High-throughput

0.261

Low

653887

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

653914

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low

470225

PT111
Protein PET111, mitochondrial

1

0

High-throughput

0.232

Low

561288

DPOLA
DNA polymerase alpha catalytic subunit A

1

0

High-throughput

0.232

Low

653829

RFA3
Replication factor A protein 3

1

0

High-throughput

0.232

Low

653833

RF1M
Peptide chain release factor 1, mitochondrial

1

0

High-throughput

0.232

Low

653836

ERG3
Delta(7)-sterol 5(6)-desaturase ERG3

1

0

High-throughput

0.232

Low

653838

ATP11
Protein ATP11, mitochondrial

1

0

High-throughput

0.232

Low

653847

RT05
Small ribosomal subunit protein uS5m

1

0

High-throughput

0.232

Low

653862

AFG3
Mitochondrial inner membrane m-AAA protease component YTA10

1

0

High-throughput

0.232

Low

653870

OYE3
NADPH dehydrogenase 3

1

0

High-throughput

0.232

Low

653875

FAR3
Factor arrest protein 3

1

0

High-throughput

0.232

Low

653877

TRF5
Poly(A) RNA polymerase protein 1

1

0

High-throughput

0.232

Low

653881

VOA1
V0 assembly protein 1

1

0

High-throughput

0.232

Low

653883

SUCA
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial

1

0

High-throughput

0.232

Low

653886

YNI9
Putative uncharacterized protein YNL089C

1

0

High-throughput

0.232

Low

653892

MLP1
Protein MLP1

1

0

High-throughput

0.232

Low

653893

YMZ2
WD repeat-containing protein YMR102C

1

0

High-throughput

0.232

Low

653896

USA1
U1 SNP1-associating protein 1

1

0

High-throughput

0.232

Low

653903

RIF2
Protein RIF2

1

0

High-throughput

0.232

Low

653905

YP078
Uncharacterized protein YPR078C

1

0

High-throughput

0.232

Low

653910

YO150
Putative uncharacterized protein YOL150C

1

0

High-throughput

0.232

Low

653912

AIM41
Altered inheritance of mitochondria protein 41, mitochondrial

1

0

High-throughput

0.232

Low

653917

RBD2
Rhomboid-type serine protease 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025