HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: HNRH2 (P55795)
Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (FTP-3) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed]
Gene: HNRNPH2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26487511, 23403292
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 595 Hs			1 449
+	Hs
		369534 ESR1_HUMAN (1-595): 0: 599: 100.00		PABP4_HUMAN (1-447): 1.01e-81: 266: 13.59
+	Hs
		368886 ESR1_HUMAN (1-595): 0: 599: 100.00		PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29
+	Hs
		370422 ESR1_HUMAN (1-595): 0: 599: 100.00		PABP3_HUMAN (1-446): 2.6e-77: 254: 12.23
+	Hs
		369739 ESR1_HUMAN (1-595): 0: 599: 100.00		PAP1L_HUMAN (1-446): 4e-77: 253: 12.42
+	Hs
		369230 ESR1_HUMAN (1-595): 0: 599: 100.00		HNRPF_HUMAN (1-434): 2.49e-60: 204: 71.72
+	Hs
		370797 ESR1_HUMAN (1-595): 0: 599: 100.00		RBM19_HUMAN (251-371): 8.32e-18: 88.3: 26.45
+	Hs
		369628 ESR1_HUMAN (1-595): 0: 599: 100.00		SART3_HUMAN (2-217): 3.71e-16: 83.3: 23.45
+	Hs
		369493 ESR1_HUMAN (1-595): 0: 599: 100.00		GRSF1_HUMAN (268-361): 1.26e-15: 80.7: 23.47
+	Hs
		369821 ESR1_HUMAN (1-595): 0: 599: 100.00		ESRP1_HUMAN (221-375): 2.36e-15: 80.2: 20.38
+	Hs
		1031409 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		PABP4_HUMAN (1-447): 1.01e-81: 266: 13.59
+	Hs
		1269600 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		PABP3_HUMAN (1-446): 2.6e-77: 254: 12.23
+	Hs
		1119140 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		PAP1L_HUMAN (1-446): 4e-77: 253: 12.42
+	Hs
		368961 ESR1_HUMAN (1-595): 0: 599: 100.00		NUCL_HUMAN (4-404): 6.61e-09: 60.2: 18.16
+	Hs
		878698 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		HNRH2_HUMAN (1-449): 1.46e-74: 242: 100.00
+	Hs
		1221286 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		RB12B_HUMAN (10-194): 6.44e-19: 91.8: 22.06
+	Hs
		1063262 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		SART3_HUMAN (2-217): 3.71e-16: 83.3: 23.45
+	Hs
		1017975 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		GRSF1_HUMAN (268-361): 1.26e-15: 80.7: 23.47
+	Hs
		1157132 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		ESRP1_HUMAN (221-375): 2.36e-15: 80.2: 20.38
+	Hs
		682640 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		HNRH3_HUMAN (10-86): 8.49e-10: 62.2: 33.77
+	Hs
		582413 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		NUCL_HUMAN (4-404): 6.61e-09: 60.2: 18.16