Protein: SPB9
Serpin B9 (Cytoplasmic antiproteinase 3) (CAP-3) (CAP3) (Peptidase inhibitor 9) (PI-9)

Gene: SPB9, SERPINB9
Organism: Homo sapiens
Interactions: 54
UniProt ID: P50453

Gene Ontology (top 5):
GO:0002020 - protease binding
GO:0002448 - mast cell mediated immunity
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005615 - extracellular space
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

518736

GRAB
Granzyme B

9

20

Small-scale

0.963

High

136671

TRAF5
TNF receptor-associated factor 5

3

8

High-throughput

0.675

High

895505

VAPA
Vesicle-associated membrane protein-associated protein A

2

0

High-throughput

0.602

High

557957

XRCC6
X-ray repair cross-complementing protein 6

2

0

High-throughput

0.588

High

895499

IGSF8
Immunoglobulin superfamily member 8

1

0

High-throughput

0.586

High

895501

IGS21
Immunoglobulin superfamily member 21

1

0

High-throughput

0.584

High

895500

TIMD4
T-cell immunoglobulin and mucin domain-containing protein 4

1

0

High-throughput

0.578

High

895476

GRAM
Granzyme M

1

20

Small-scale

0.575

High

895480

KPCE
Protein kinase C epsilon type

2

3

High-throughput

0.571

High

248385

GDF9
Growth/differentiation factor 9

1

8

High-throughput

0.541

High

280551

PR40A
Pre-mRNA-processing factor 40 homolog A

1

1

High-throughput

0.541

High

413424

P53
Cellular tumor antigen p53

1

1

High-throughput

0.541

High

895479

EF1A1
Elongation factor 1-alpha 1

1

3

High-throughput

0.541

High

895481

TLE1
Transducin-like enhancer protein 1

1

3

High-throughput

0.541

High

895483

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

1

High-throughput

0.541

High

895485

TBB2A
Tubulin beta-2A chain

1

1

High-throughput

0.541

High

895488

SETB1
Histone-lysine N-methyltransferase SETDB1

1

1

High-throughput

0.541

High

895493

CSN6
COP9 signalosome complex subunit 6

1

1

High-throughput

0.541

High

895504

BRD7
Bromodomain-containing protein 7

1

1

High-throughput

0.541

High

895510

PKHM1
Pleckstrin homology domain-containing family M member 1

1

2

High-throughput

0.541

High

895497

ACTT1
Actin-related protein T1

1

1

High-throughput

0.536

High

895508

RCL1
RNA 3'-terminal phosphate cyclase-like protein

1

2

High-throughput

0.536

High

408744

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.518

High

736908

GBP2
Guanylate-binding protein 2

1

0

High-throughput

0.518

High

895484

U119A
Protein unc-119 homolog A

1

0

High-throughput

0.518

High

895486

DPYL1
Dihydropyrimidinase-related protein 1

1

0

High-throughput

0.518

High

895489

RBM48
RNA-binding protein 48

1

0

High-throughput

0.518

High

895494

UBR1
E3 ubiquitin-protein ligase UBR1

1

0

High-throughput

0.518

High

895506

ERG28
Ergosterol biosynthetic protein 28 homolog

1

0

High-throughput

0.518

High

895507

ZHX1
Zinc fingers and homeoboxes protein 1

1

0

High-throughput

0.518

High

895509

MED31
Mediator of RNA polymerase II transcription subunit 31

1

0

High-throughput

0.518

High

895492

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

1

0

High-throughput

0.513

High

712838

CASP1
Caspase-1

1

8

Small-scale

0.501

High

885685

CASP4
Caspase-4

1

8

Small-scale

0.501

High

895482

SIAT6
CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase

1

4

High-throughput

0.489

High

895495

FA24B
Protein FAM24B

1

1

High-throughput

0.489

High

241110

PRKN
E3 ubiquitin-protein ligase parkin

1

5

High-throughput

0.479

High

385566

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

2

High-throughput

0.479

High

798852

BRCA1
Breast cancer type 1 susceptibility protein

1

8

High-throughput

0.479

High

887845

MCM2
DNA replication licensing factor MCM2

1

6

High-throughput

0.479

High

895478

CD81
CD81 antigen

1

3

High-throughput

0.479

High

895487

CASP8
Caspase-8

1

8

Small-scale

0.479

High

895498

CASPA
Caspase-10

1

8

Small-scale

0.479

High

895490

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.460

High

487096

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

667653

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.458

High

895496

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

2132

PAL4C
Peptidyl-prolyl cis-trans isomerase A-like 4C

1

3

High-throughput

0.445

High

404730

PRIO
Major prion protein

1

2

High-throughput

0.445

High

895477

TERA
Transitional endoplasmic reticulum ATPase

1

2

High-throughput

0.445

High

895491

RIF1
Telomere-associated protein RIF1

1

0

High-throughput

0.438

High

105586

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

895503

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

0

High-throughput

0.282

High

895502

TX101
Testis-expressed protein 101

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025