HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: TEBP (Q15185)
Prostaglandin E synthase 3 (EC 5.3.99.3) (Cytosolic prostaglandin E2 synthase) (cPGES) (Hsp90 co-chaperone) (Progesterone receptor complex p23) (Telomerase-binding protein p23)
Gene: PTGES3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	27483141, 9222609, 18388150
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0007165 - signal transduction GO:0032991 - protein-containing complex and 1 others more... GO:0048144 - fibroblast proliferation
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 595 Hs			1 160
+	Hs
		370591 ESR1_HUMAN (1-595): 0: 599: 100.00		HACD3_HUMAN (4-115): 1.97e-34: 125: 22.61
+	Hs
		1269794 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		HACD3_HUMAN (4-115): 1.97e-34: 125: 22.61
+	Hs
		377334 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		TEBP_HUMAN (1-160): 4.35e-55: 172: 100.00
+	Hs
		437641 MCR_HUMAN (21-554): 3.98e-103: 335: 22.01		TEBP_HUMAN (1-160): 4.35e-55: 172: 100.00
+	Hs
		320232 ERR2_HUMAN (92-547): 4.3e-116: 354: 34.86		HACD3_HUMAN (4-115): 1.97e-34: 125: 22.61
+	Hs
		414504 PRGR_HUMAN (183-508): 6.92e-44: 170: 32.14		TEBP_HUMAN (1-160): 4.35e-55: 172: 100.00
+	Hs
		487452 ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16		TEBP_HUMAN (1-160): 4.35e-55: 172: 100.00