HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: DDX54 (Q8TDD1)
ATP-dependent RNA helicase DDX54 (EC 3.6.4.13) (ATP-dependent RNA helicase DP97) (DEAD box RNA helicase 97 kDa) (DEAD box protein 54)
Gene: DDX54

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 0.60 0.626

The method score is based on:

Property Details
Experiments 12466272, 21182205
Identification Methods pull down, two hybrid, affinity chromatography technology, cosedimentation through density gradient
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005794 - Golgi apparatus
GO:0016020 - membrane
GO:0030331 - nuclear estrogen receptor binding
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 595
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024