HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: COR1C (Q9ULV4)
Coronin-1C (Coronin-3) (hCRNN4)
Gene: CORO1C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.672

Property	Details
Experiments	26487511, 31527615, 33731348, unassigned1953
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 595 Hs			1 474
+	Hs
		1269916 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		COR1C_HUMAN (1-474): 4e-137: 404: 100.00
+	Hs
		1269474 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		COR1B_HUMAN (2-472): 1.75e-120: 362: 72.14
+	Hs
		678296 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		COR1A_HUMAN (2-467): 2.74e-113: 343: 64.24
+	Hs
		369695 ESR1_HUMAN (1-595): 0: 599: 100.00		RBBP7_HUMAN (14-341): 1.13e-35: 139: 18.94
+	Hs
		369483 ESR1_HUMAN (1-595): 0: 599: 100.00		RBBP4_HUMAN (129-345): 4.31e-24: 106: 15.39
+	Hs
		369305 ESR1_HUMAN (1-595): 0: 599: 100.00		WDR5_HUMAN (257-397): 3.67e-15: 78.4: 8.39
+	Hs
		369932 ESR1_HUMAN (1-595): 0: 599: 100.00		WDR5B_HUMAN (250-381): 2.07e-14: 76.1: 9.70
+	Hs
		1083334 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		RBBP7_HUMAN (14-341): 1.13e-35: 139: 18.94
+	Hs
		903403 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		WDR5_HUMAN (257-397): 3.67e-15: 78.4: 8.39
+	Hs
		488008 RARA_HUMAN (81-545): 1.35e-102: 320: 22.37		SNR40_HUMAN (160-435): 1.36e-38: 145: 11.87
+	Mm
		1141930 ERR2_MOUSE (92-547): 6.98e-113: 345: 34.42		RBBP4_MOUSE (129-345): 4.31e-24: 106: 15.39
+	Dm
		836363 HNF4_DROME (79-589): 8.19e-106: 336: 21.40		CAF1_DROME (129-345): 4.97e-25: 108: 15.39
+	Hs
		490098 COT1_HUMAN (105-555): 1.65e-109: 336: 23.62		RBBP4_HUMAN (129-345): 4.31e-24: 106: 15.39
+	Hs
		782513 HNF4A_HUMAN (146-592): 2.13e-118: 361: 20.58		WDR5_HUMAN (257-397): 3.67e-15: 78.4: 8.39
+	Hs
		874390 NR1H2_HUMAN (103-548): 4.02e-105: 326: 21.26		COR2A_HUMAN (4-212): 5.87e-25: 109: 10.46
+	Mm
		903664 ERR2_MOUSE (92-547): 6.98e-113: 345: 34.42		WDR5_MOUSE (257-397): 3.67e-15: 78.4: 8.39
+	Hs
		377481 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		WDR17_HUMAN (79-205): 4.97e-10: 64.3: 29.69
+	Hs
		740487 PPARG_HUMAN (55-546): 2.12e-100: 316: 20.35		WDR5_HUMAN (257-397): 3.67e-15: 78.4: 8.39
+	Hs
		414495 PRGR_HUMAN (183-508): 6.92e-44: 170: 32.14		RBBP4_HUMAN (129-345): 4.31e-24: 106: 15.39
+	Hs
		487288 ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16		WDR5_HUMAN (257-397): 3.67e-15: 78.4: 8.39