HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: HYOU1 (Q9Y4L1)
Hypoxia up-regulated protein 1 (150 kDa oxygen-regulated protein) (ORP-150) (170 kDa glucose-regulated protein) (GRP-170) (Heat shock protein family H member 4)
Gene: HYOU1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	25604459
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 595 Hs			1 999
+	Hs
		370116 ESR1_HUMAN (1-595): 0: 599: 100.00		HS105_HUMAN (33-960): 0: 812: 24.46
+	Hs
		320786 ESR1_HUMAN (1-595): 0: 599: 100.00		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		369085 ESR1_HUMAN (1-595): 0: 599: 100.00		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Hs
		1270023 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		1267724 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		HS105_HUMAN (33-960): 0: 812: 24.46
+	Hs
		377830 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		714336 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Hs
		377137 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Rn
		291976 GCR_RAT (5-557): 9.7e-106: 338: 22.68		HSP74_RAT (33-964): 0: 787: 25.53
+	Hs
		369084 ESR1_HUMAN (1-595): 0: 599: 100.00		HS71L_HUMAN (682-814): 9.92e-31: 131: 15.04
+	Hs
		368878 ESR1_HUMAN (1-595): 0: 599: 100.00		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		369248 ESR1_HUMAN (1-595): 0: 599: 100.00		HSP72_HUMAN (682-814): 8.57e-30: 128: 16.54
+	Hs
		368938 ESR1_HUMAN (1-595): 0: 599: 100.00		HSP76_HUMAN (682-813): 1.1e-27: 121: 19.70
+	Hs
		714036 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		HS71L_HUMAN (682-814): 9.92e-31: 131: 15.04
+	Hs
		504498 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		564142 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		HSP76_HUMAN (682-813): 1.1e-27: 121: 19.70
+	Hs
		320162 ERR2_HUMAN (92-547): 4.3e-116: 354: 34.86		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		377052 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		504003 NR1H3_HUMAN (99-548): 6.2e-112: 343: 20.49		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		503444 NR4A1_HUMAN (64-549): 2.81e-105: 331: 24.54		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42