Interactor 1: FA11 (P03951)
Coagulation factor XI (FXI) (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) [Cleaved into: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain]
Gene: F11

Interactor 2: FA11 (P03951)
Coagulation factor XI (FXI) (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) [Cleaved into: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain]
Gene: F11

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.815

The method score is based on:

Property Details
Experiments 16699514, 17884987
Identification Methods x-ray crystallography, nuclear magnetic resonance, transmission electron microscopy, x ray scattering, dynamic light scattering
Interaction Type covalent binding, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PAN_1~PAN_1, PAN_1~Trypsin, Trypsin~Trypsin
Common GO terms GO:0004252 - serine-type endopeptidase activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0007596 - blood coagulation
and 6 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 625
Hs

1 625
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+ Dm

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Last updated: 15 Jul 2024