HitPredict

Interactor 1: CFAD (P03953)
Complement factor D (EC 3.4.21.46) (28 kDa adipocyte protein) (Adipsin) (C3 convertase activator) (Properdin factor D)
Gene: Cfd

Interactor 2: TMX4 (Q8C0L0)
Thioredoxin-related transmembrane protein 4 (Thioredoxin domain-containing protein 13)
Gene: TMX4

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	30550785
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 259 Mm			1 335
+	Hs
		409557 HEPS_HUMAN (15-259): 1.34e-98: 295: 30.68		TMX4_HUMAN (1-334): 1.09e-83: 258: 78.51
+	Mm
		372249 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		TMX1_MOUSE (31-237): 1.73e-70: 222: 43.00
+	Hs
		1198170 TM11B_HUMAN (13-253): 7.08e-99: 296: 31.73		TMX1_HUMAN (31-237): 2.57e-70: 222: 43.54
+	Mm
		372340 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		PDIA6_MOUSE (16-281): 6.39e-61: 202: 17.41
+	Hs
		178003 TMPS2_HUMAN (9-256): 4.56e-97: 294: 29.34		TMX1_HUMAN (31-237): 2.57e-70: 222: 43.54
+	Hs
		1330216 TMPS4_HUMAN (9-252): 1.75e-97: 293: 35.06		TMX1_HUMAN (31-237): 2.57e-70: 222: 43.54
+	Mm
		371851 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		QSOX2_MOUSE (10-270): 1.67e-42: 158: 13.84
+	Mm
		372332 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		PDIA5_MOUSE (9-289): 5.87e-40: 148: 10.77
+	Mm
		372298 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		TXND5_MOUSE (12-138): 8.64e-34: 130: 21.21
+	Hs
		409518 HEPS_HUMAN (15-259): 1.34e-98: 295: 30.68		PDIA5_HUMAN (9-289): 1.65e-38: 145: 10.44
+	Mm
		371494 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		PDIA1_MOUSE (23-133): 4.11e-25: 107: 16.95
+	Mm
		371577 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		PDIA3_MOUSE (121-254): 2.16e-14: 75.7: 10.88
+	Mm
		372572 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		DJC10_MOUSE (38-274): 3.78e-13: 72.2: 13.39
+	Mm
		371488 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		PDIA4_MOUSE (123-270): 3.96e-11: 66: 9.09
+	Hs
		1198135 TM11B_HUMAN (13-253): 7.08e-99: 296: 31.73		TMX3_HUMAN (51-144): 1.32e-15: 79.4: 25.00
+	Hs
		1295326 TMPS4_HUMAN (9-252): 1.75e-97: 293: 35.06		TMX3_HUMAN (51-144): 1.32e-15: 79.4: 25.00
+	Hs
		531888 TM11B_HUMAN (13-253): 7.08e-99: 296: 31.73		PDIA4_HUMAN (149-326): 9.13e-12: 68: 7.85
+	Hs
		177808 TMPS2_HUMAN (9-256): 4.56e-97: 294: 29.34		PDIA4_HUMAN (149-326): 9.13e-12: 68: 7.85
+	Hs
		531997 TMPS4_HUMAN (9-252): 1.75e-97: 293: 35.06		PDIA4_HUMAN (149-326): 9.13e-12: 68: 7.85
+	Hs
		1162567 KLK15_HUMAN (16-256): 3.77e-97: 286: 36.61		TXD11_HUMAN (18-165): 2.69e-13: 73: 15.29