Protein: MGAP
MAX gene-associated protein (MAX dimerization protein 5)

Gene: MGAP, MGA
Organism: Homo sapiens
Interactions: 218
UniProt ID: Q8IWI9

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001708 - cell fate specification
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

959614

MAX
Protein max

6

6

High-throughput

0.955

High

372506

MYC
Myc proto-oncogene protein

4

5

High-throughput

0.873

High

998515

H31
Histone H3.1

4

2

High-throughput

0.873

High

1310140

MLX
Max-like protein X

2

4

High-throughput

0.811

High

1310088

RYBP
RING1 and YY1-binding protein

7

3

High-throughput

0.747

High

1097408

CBX3
Chromobox protein homolog 3

6

9

High-throughput

0.737

High

965076

WDR5
WD repeat-containing protein 5

6

1

Small-scale

0.735

High

1310082

YAF2
YY1-associated factor 2

6

3

High-throughput

0.733

High

1310114

RING2
E3 ubiquitin-protein ligase RING2

6

13

Small-scale

0.733

High

1310124

PCGF6
Polycomb group RING finger protein 6

6

14

High-throughput

0.733

High

282746

E2F6
Transcription factor E2F6

5

4

High-throughput

0.718

High

1310100

LMBL2
Lethal(3)malignant brain tumor-like protein 2

4

3

High-throughput

0.704

High

1109871

HDAC1
Histone deacetylase 1

4

7

High-throughput

0.699

High

610398

PRS6A
26S proteasome regulatory subunit 6A

3

1

High-throughput

0.667

High

1233900

WBP2L
Postacrosomal sheath WW domain-binding protein

3

1

High-throughput

0.667

High

1310086

MIER2
Mesoderm induction early response protein 2

3

13

High-throughput

0.667

High

960480

PSME3
Proteasome activator complex subunit 3

3

0

High-throughput

0.638

High

1310147

CARD8
Caspase recruitment domain-containing protein 8

3

0

High-throughput

0.638

High

1014153

CBX1
Chromobox protein homolog 1

2

9

High-throughput

0.628

High

1055821

RING1
E3 ubiquitin-protein ligase RING1

2

13

High-throughput

0.628

High

1092997

CDC16
Cell division cycle protein 16 homolog

2

2

High-throughput

0.628

High

1122843

TFDP1
Transcription factor Dp-1

2

1

High-throughput

0.628

High

1310122

ZN692
Zinc finger protein 692

2

2

High-throughput

0.628

High

833752

KDM5C
Lysine-specific demethylase 5C

2

4

Small-scale

0.618

High

210047

CRX
Cone-rod homeobox protein

1

19

High-throughput

0.618

High

581688

MYOD1
Myoblast determination protein 1

1

3

High-throughput

0.618

High

685258

PAX6
Paired box protein Pax-6

1

12

High-throughput

0.618

High

754904

H2B1B
Histone H2B type 1-B

1

1

High-throughput

0.618

High

877531

LHX1
LIM/homeobox protein Lhx1

1

8

High-throughput

0.618

High

895750

LHX2
LIM/homeobox protein Lhx2

1

11

High-throughput

0.618

High

980905

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.618

High

1017005

H33
Histone H3.3

1

2

High-throughput

0.618

High

1037870

HEN1
Helix-loop-helix protein 1

1

3

High-throughput

0.618

High

1050741

MAD1
Max dimerization protein 1

1

5

Small-scale

0.618

High

1052888

HME1
Homeobox protein engrailed-1

1

20

High-throughput

0.618

High

1310097

ATOH1
Transcription factor ATOH1

1

2

Small-scale

0.618

High

1310099

LHX4
LIM/homeobox protein Lhx4

1

8

High-throughput

0.618

High

1310127

ADNP
Activity-dependent neuroprotector homeobox protein

1

1

High-throughput

0.618

High

1310137

LHX3
LIM/homeobox protein Lhx3

1

10

High-throughput

0.618

High

1004795

RNF4
E3 ubiquitin-protein ligase RNF4

2

1

High-throughput

0.611

High

1310142

KLF15
Krueppel-like factor 15

2

13

High-throughput

0.611

High

1310144

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

2

4

High-throughput

0.611

High

1119576

NFYC
Nuclear transcription factor Y subunit gamma

1

0

High-throughput

0.586

High

474113

NFIC
Nuclear factor 1 C-type

2

20

High-throughput

0.584

High

558255

XRCC6
X-ray repair cross-complementing protein 6

2

4

High-throughput

0.584

High

1133517

NFIX
Nuclear factor 1 X-type

2

20

High-throughput

0.584

High

1185919

PCGF3
Polycomb group RING finger protein 3

2

13

High-throughput

0.584

High

1310083

SLX4
Structure-specific endonuclease subunit SLX4

2

6

High-throughput

0.584

High

1310089

NIN
Ninein

2

0

High-throughput

0.559

High

1310126

CAD19
Cadherin-19

2

1

High-throughput

0.558

High

1050809

PTN12
Tyrosine-protein phosphatase non-receptor type 12

2

0

High-throughput

0.547

High

156642

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

3

High-throughput

0.536

High

216482

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

1

High-throughput

0.536

High

625478

CSK22
Casein kinase II subunit alpha'

1

2

High-throughput

0.536

High

853335

CBX5
Chromobox protein homolog 5

1

9

High-throughput

0.536

High

854153

KI67
Proliferation marker protein Ki-67

1

4

High-throughput

0.536

High

997834

CSK21
Casein kinase II subunit alpha

1

2

High-throughput

0.536

High

1099720

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

2

High-throughput

0.536

High

1122886

TFDP2
Transcription factor Dp-2

1

1

High-throughput

0.536

High

1310085

PIAS4
E3 SUMO-protein ligase PIAS4

1

1

High-throughput

0.536

High

1310101

TRI52
E3 ubiquitin-protein ligase TRIM52

1

2

High-throughput

0.536

High

1161931

H31T
Histone H3.1t

1

2

High-throughput

0.527

High

1218377

ARHGG
Rho guanine nucleotide exchange factor 16

2

1

High-throughput

0.521

High

1295380

MF2L2
Probable guanine nucleotide exchange factor MCF2L2

2

3

High-throughput

0.521

High

279413

TULP3
Tubby-related protein 3

1

0

High-throughput

0.518

High

930746

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

0

High-throughput

0.513

High

1156305

HSPB2
Heat shock protein beta-2

1

0

High-throughput

0.513

High

1235462

IFIX
Pyrin and HIN domain-containing protein 1

1

0

High-throughput

0.513

High

1153976

SMAD1
Mothers against decapentaplegic homolog 1

1

6

High-throughput

0.508

High

549632

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

1

High-throughput

0.489

High

954529

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

1

High-throughput

0.489

High

1310084

CRBG2
Beta/gamma crystallin domain-containing protein 2

1

4

High-throughput

0.489

High

143453

E2F3
Transcription factor E2F3

1

4

Small-scale

0.481

High

344557

LSM8
U6 snRNA-associated Sm-like protein LSm8

1

1

High-throughput

0.481

High

1029110

E2F1
Transcription factor E2F1

1

4

Small-scale

0.481

High

1156762

E2F4
Transcription factor E2F4

1

4

Small-scale

0.481

High

129762

CBX4
E3 SUMO-protein ligase CBX4

1

10

High-throughput

0.479

High

143104

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

190986

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

5

High-throughput

0.479

High

242209

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

246739

KDM1A
Lysine-specific histone demethylase 1A

1

6

High-throughput

0.479

High

260152

BRD4
Bromodomain-containing protein 4

1

8

High-throughput

0.479

High

285352

EED
Polycomb protein EED

1

5

High-throughput

0.479

High

334568

ZBT7A
Zinc finger and BTB domain-containing protein 7A

1

3

Small-scale

0.479

High

339795

KLF8
Krueppel-like factor 8

1

13

High-throughput

0.479

High

349146

LATS1
Serine/threonine-protein kinase LATS1

1

2

High-throughput

0.479

High

414160

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

487502

PARP1
Poly [ADP-ribose] polymerase 1

1

2

High-throughput

0.479

High

519399

MYB
Transcriptional activator Myb

1

2

High-throughput

0.479

High

520188

ANDR
Androgen receptor

1

7

High-throughput

0.479

High

538433

EGR2
E3 SUMO-protein ligase EGR2

1

3

High-throughput

0.479

High

577463

ETS1
Protein C-ets-1

1

6

High-throughput

0.479

High

675573

TYY1
Transcriptional repressor protein YY1

1

3

High-throughput

0.479

High

703168

TEAD1
Transcriptional enhancer factor TEF-1

1

2

High-throughput

0.479

High

739004

ELF1
ETS-related transcription factor Elf-1

1

8

High-throughput

0.479

High

765682

BMI1
Polycomb complex protein BMI-1

1

12

High-throughput

0.479

High

766100

PCGF2
Polycomb group RING finger protein 2

1

12

High-throughput

0.479

High

775880

HNF1B
Hepatocyte nuclear factor 1-beta

1

13

High-throughput

0.479

High

832543

ETV3
ETS translocation variant 3

1

7

High-throughput

0.479

High

833989

HNF4A
Hepatocyte nuclear factor 4-alpha

1

4

High-throughput

0.479

High

837066

ELK3
ETS domain-containing protein Elk-3

1

8

High-throughput

0.479

High

862282

YAP1
Transcriptional coactivator YAP1

1

2

High-throughput

0.479

High

881560

CDK8
Cyclin-dependent kinase 8

1

3

High-throughput

0.479

High

944700

KLF3
Krueppel-like factor 3

1

12

High-throughput

0.479

High

979944

H4
Histone H4

1

2

High-throughput

0.479

High

1006856

PHC1
Polyhomeotic-like protein 1

1

6

High-throughput

0.479

High

1040060

PAX2
Paired box protein Pax-2

1

12

High-throughput

0.479

High

1087856

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

1118659

KLF9
Krueppel-like factor 9

1

13

High-throughput

0.479

High

1118733

KLF5
Krueppel-like factor 5

1

12

High-throughput

0.479

High

1129644

MDC1
Mediator of DNA damage checkpoint protein 1

1

7

High-throughput

0.479

High

1130096

SMC1A
Structural maintenance of chromosomes protein 1A

1

1

High-throughput

0.479

High

1132209

CBX2
Chromobox protein homolog 2

1

10

High-throughput

0.479

High

1141206

BRD3
Bromodomain-containing protein 3

1

10

High-throughput

0.479

High

1152708

ELF2
ETS-related transcription factor Elf-2

1

7

High-throughput

0.479

High

1204617

BCORL
BCL-6 corepressor-like protein 1

1

4

High-throughput

0.479

High

1235648

NIPBL
Nipped-B-like protein

1

7

High-throughput

0.479

High

1250610

BCOR
BCL-6 corepressor

1

4

High-throughput

0.479

High

1277176

POGZ
Pogo transposable element with ZNF domain

1

3

High-throughput

0.479

High

1286242

PCGF5
Polycomb group RING finger protein 5

1

13

High-throughput

0.479

High

1310081

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

1310087

STAG2
Cohesin subunit SA-2

1

1

High-throughput

0.479

High

1310091

ZBT38
Zinc finger and BTB domain-containing protein 38

1

3

Small-scale

0.479

High

1310092

NUP43
Nucleoporin Nup43

1

5

High-throughput

0.479

High

1310093

KDM2B
Lysine-specific demethylase 2B

1

3

High-throughput

0.479

High

1310094

SP7
Transcription factor Sp7

1

9

High-throughput

0.479

High

1310096

ESR2
Estrogen receptor beta

1

7

High-throughput

0.479

High

1310103

PF21A
PHD finger protein 21A

1

8

High-throughput

0.479

High

1310104

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

4

High-throughput

0.479

High

1310106

CDCA5
Sororin

1

1

High-throughput

0.479

High

1310107

CHAP1
Chromosome alignment-maintaining phosphoprotein 1

1

11

High-throughput

0.479

High

1310113

CIC
Protein capicua homolog

1

17

High-throughput

0.479

High

1310115

FEV
Protein FEV

1

6

High-throughput

0.479

High

1310116

ELF4
ETS-related transcription factor Elf-4

1

8

High-throughput

0.479

High

1310117

KLF6
Krueppel-like factor 6

1

15

High-throughput

0.479

High

1310118

ANM1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.479

High

1310120

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

3

High-throughput

0.479

High

1310121

PCGF1
Polycomb group RING finger protein 1

1

12

High-throughput

0.479

High

1310123

KLF16
Krueppel-like factor 16

1

11

High-throughput

0.479

High

1310131

CBX8
Chromobox protein homolog 8

1

10

High-throughput

0.479

High

1310136

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

2

High-throughput

0.479

High

1310138

ZMYM2
Zinc finger MYM-type protein 2

1

5

High-throughput

0.479

High

1310139

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1310141

XPO7
Exportin-7

1

2

High-throughput

0.479

High

1310143

RCOR1
REST corepressor 1

1

17

High-throughput

0.479

High

1310145

SMC3
Structural maintenance of chromosomes protein 3

1

1

High-throughput

0.479

High

1310148

KLF12
Krueppel-like factor 12

1

12

High-throughput

0.479

High

257478

PAGE4
P antigen family member 4

1

0

High-throughput

0.458

High

378506

IL1A
Interleukin-1 alpha

1

0

Small-scale

0.458

High

533948

IRF1
Interferon regulatory factor 1

1

0

High-throughput

0.458

High

589099

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

664773

CCND1
G1/S-specific cyclin-D1

1

0

High-throughput

0.458

High

695884

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

697167

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

768595

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

799970

COIL
Coilin

1

0

High-throughput

0.458

High

869057

TISD
mRNA decay activator protein ZFP36L2

1

0

High-throughput

0.458

High

897332

CDK7
Cyclin-dependent kinase 7

1

0

High-throughput

0.458

High

970743

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

971750

1433E
14-3-3 protein epsilon

1

0

Small-scale

0.458

High

1026458

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

1177593

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

0

High-throughput

0.458

High

1212414

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.458

High

1276454

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1279192

WAPL
Wings apart-like protein homolog

1

0

High-throughput

0.458

High

1310095

CNOT9
CCR4-NOT transcription complex subunit 9

1

0

High-throughput

0.458

High

1310112

ALKB3
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3

1

0

Small-scale

0.458

High

1310125

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

1310128

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1310129

AKTIP
AKT-interacting protein

1

0

High-throughput

0.458

High

1310132

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

1310134

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1310135

KANL3
KAT8 regulatory NSL complex subunit 3

1

0

High-throughput

0.458

High

1310146

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.458

High

1310150

SCC4
MAU2 chromatid cohesion factor homolog

1

0

High-throughput

0.458

High

106233

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

320568

FARP2
FERM, ARHGEF and pleckstrin domain-containing protein 2

1

1

High-throughput

0.437

High

472323

CFAH
Complement factor H

1

1

Small-scale

0.437

High

533821

MCF2
Proto-oncogene DBL

1

3

High-throughput

0.437

High

914013

CHIO
Beta-chimaerin

1

1

High-throughput

0.437

High

1071173

ARL16
ADP-ribosylation factor-like protein 16

1

1

High-throughput

0.437

High

1092735

RHG05
Rho GTPase-activating protein 5

1

1

High-throughput

0.437

High

1141762

EEA1
Early endosome antigen 1

1

2

High-throughput

0.437

High

1310080

DHX40
Probable ATP-dependent RNA helicase DHX40

1

1

High-throughput

0.437

High

1310098

ARHG1
Rho guanine nucleotide exchange factor 1

1

2

High-throughput

0.437

High

1310105

RNF31
E3 ubiquitin-protein ligase RNF31

1

2

High-throughput

0.437

High

1310109

SNX27
Sorting nexin-27

1

1

High-throughput

0.437

High

1310130

FBRS
Probable fibrosin-1

1

4

High-throughput

0.437

High

1295461

S13A5
Na(+)/citrate cotransporter

1

0

High-throughput

0.426

High

58859

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

1

High-throughput

0.407

High

87500

OSCRI
SCRIB overlapping open reading frame protein

1

1

High-throughput

0.407

High

1310108

Q96KY9
CDH19 protein

1

1

High-throughput

0.407

High

1180399

KLH40
Kelch-like protein 40

2

0

High-throughput

0.328

High

1310133

ASB6
Ankyrin repeat and SOCS box protein 6

2

0

High-throughput

0.328

High

787563

TNR3
Tumor necrosis factor receptor superfamily member 3

2

0

High-throughput

0.318

High

1257244

RFPLB
Ret finger protein-like 4B

2

0

High-throughput

0.318

High

239121

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.279

Low

391336

FRIL
Ferritin light chain

1

0

High-throughput

0.279

Low

596501

CTLA4
Cytotoxic T-lymphocyte protein 4

1

0

High-throughput

0.279

Low

1203716

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.279

Low

1310110

LURA1
Leucine rich adaptor protein 1

1

0

High-throughput

0.279

Low

1310111

TMM74
Transmembrane protein 74

1

0

High-throughput

0.279

Low

1310119

DHB14
L-fucose dehydrogenase

1

0

High-throughput

0.279

Low

1310149

S12A7
Solute carrier family 12 member 7

1

0

High-throughput

0.269

Low

213365

ARHG9
Rho guanine nucleotide exchange factor 9

1

0

High-throughput

0.249

Low

272305

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.249

Low

293979

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

323476

TRI37
E3 ubiquitin-protein ligase TRIM37

1

0

High-throughput

0.249

Low

346039

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.249

Low

390655

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.249

Low

886292

ARL4D
ADP-ribosylation factor-like protein 4D

1

0

High-throughput

0.249

Low

1215695

RC3H1
Roquin-1

1

0

High-throughput

0.249

Low

1226462

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low

1246871

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.249

Low

1295480

MIB1
E3 ubiquitin-protein ligase MIB1

1

0

High-throughput

0.249

Low

1310090

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.249

Low

1310102

KIFC2
Kinesin-like protein KIFC2

1

0

High-throughput

0.249

Low

132918

S28A1
Sodium/nucleoside cotransporter 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025