HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: RBM14 (Q96PK6)
RNA-binding protein 14 (Paraspeckle protein 2) (PSP2) (RNA-binding motif protein 14) (RRM-containing coactivator activator/modulator) (Synaptotagmin-interacting protein) (SYT-interacting protein)
Gene: RBM14

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	29467282, 35013218, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 669
+	Hs
		373043 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		RBM4_HUMAN (1-349): 7.23e-60: 206: 27.22
+	Hs
		372975 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		RBM4B_HUMAN (1-349): 7e-59: 204: 27.71
+	Hs
		371033 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		PABP1_HUMAN (3-555): 1.63e-35: 144: 14.36
+	Hs
		371897 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		ELAV2_HUMAN (4-154): 1.38e-16: 83.8: 25.15
+	Hs
		371211 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		ELAV4_HUMAN (4-154): 5.21e-16: 82.3: 24.56
+	Hs
		371994 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		HNRPD_HUMAN (76-161): 1.03e-15: 81.2: 22.45
+	Hs
		406527 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		RBM14_HUMAN (1-669): 1.6e-66: 232: 100.00
+	Hs
		371939 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		PABP4_HUMAN (71-151): 5.62e-10: 64.6: 23.60
+	Hs
		406560 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		RBM4B_HUMAN (1-349): 7e-59: 204: 27.71
+	Hs
		319075 K0754_HUMAN (47-360): 5.63e-40: 155: 12.62		RBM14_HUMAN (1-669): 1.6e-66: 232: 100.00
+	Hs
		406478 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		MSI2H_HUMAN (2-292): 1.09e-51: 183: 18.01
+	Hs
		405731 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		PABP1_HUMAN (3-555): 1.63e-35: 144: 14.36
+	Hs
		406121 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		ELAV2_HUMAN (4-154): 1.38e-16: 83.8: 25.15
+	Hs
		405810 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		ELAV4_HUMAN (4-154): 5.21e-16: 82.3: 24.56
+	Hs
		406165 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		HNRPD_HUMAN (76-161): 1.03e-15: 81.2: 22.45
+	Hs
		406141 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		PABP4_HUMAN (71-151): 5.62e-10: 64.6: 23.60