Interactor 1: HMDH (P04035)
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) (EC 1.1.1.34)
Gene: HMGCR

Interactor 2: RN139 (Q8WU17)
E3 ubiquitin-protein ligase RNF139 (EC 2.3.2.27) (RING finger protein 139) (RING-type E3 ubiquitin transferase RNF139) (Translocation in renal carcinoma on chromosome 8 protein)
Gene: RNF139

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 22143767
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 888
Hs

1 664
+ Hs
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+ Dm
+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024