Protein: PI15
Peptidase inhibitor 15 (PI-15) (25 kDa trypsin inhibitor) (p25TI) (Cysteine-rich secretory protein 8) (CRISP-8) (SugarCrisp)

Gene: PI15
Organism: Homo sapiens
Interactions: 84
UniProt ID: O43692

Gene Ontology (top 5):
GO:0005615 - extracellular space
GO:0030414 - peptidase inhibitor activity
GO:0070062 - extracellular exosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

136751

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

4

High-throughput

0.536

High

144033

MA2B1
Lysosomal alpha-mannosidase

1

2

High-throughput

0.536

High

183204

LAMA5
Laminin subunit alpha-5

1

9

High-throughput

0.536

High

224461

TSP1
Thrombospondin-1

1

3

High-throughput

0.536

High

224462

BIP
Endoplasmic reticulum chaperone BiP

1

5

High-throughput

0.536

High

224463

LAMC1
Laminin subunit gamma-1

1

7

High-throughput

0.536

High

224464

BMP1
Bone morphogenetic protein 1

1

3

High-throughput

0.536

High

224469

GALNS
N-acetylgalactosamine-6-sulfatase

1

3

High-throughput

0.536

High

224473

SPHM
N-sulphoglucosamine sulphohydrolase

1

3

High-throughput

0.536

High

224476

ANAG
Alpha-N-acetylglucosaminidase

1

1

High-throughput

0.536

High

224477

LAMB2
Laminin subunit beta-2

1

6

High-throughput

0.536

High

224478

PGBM
Basement membrane-specific heparan sulfate proteoglycan core protein

1

3

High-throughput

0.536

High

224479

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

1

High-throughput

0.536

High

224490

METRL
Meteorin-like protein

1

2

High-throughput

0.536

High

224492

CSPG4
Chondroitin sulfate proteoglycan 4

1

4

High-throughput

0.536

High

224494

THSD4
Thrombospondin type-1 domain-containing protein 4

1

3

High-throughput

0.536

High

224498

CILP2
Cartilage intermediate layer protein 2

1

1

High-throughput

0.536

High

224505

PCSK9
Proprotein convertase subtilisin/kexin type 9

1

3

High-throughput

0.536

High

224506

UXS1
UDP-glucuronic acid decarboxylase 1

1

1

High-throughput

0.536

High

224507

SORL
Sortilin-related receptor

1

5

High-throughput

0.536

High

224510

PCSK5
Proprotein convertase subtilisin/kexin type 5

1

3

High-throughput

0.536

High

224515

GDF15
Growth/differentiation factor 15

1

1

High-throughput

0.536

High

224516

CHID1
Chitinase domain-containing protein 1

1

1

High-throughput

0.536

High

224520

CHRD
Chordin

1

8

High-throughput

0.536

High

224526

PLXA1
Plexin-A1

1

4

High-throughput

0.536

High

224527

METRN
Meteorin

1

2

High-throughput

0.536

High

224529

MA2B2
Epididymis-specific alpha-mannosidase

1

2

High-throughput

0.536

High

224468

KPYR
Pyruvate kinase PKLR

1

0

High-throughput

0.513

High

224472

MMP15
Matrix metalloproteinase-15

1

0

High-throughput

0.513

High

224483

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.513

High

224487

ERFE
Erythroferrone

1

0

High-throughput

0.513

High

224496

BMP8A
Bone morphogenetic protein 8A

1

0

High-throughput

0.513

High

224511

EXT2
Exostosin-2

1

0

High-throughput

0.513

High

224518

TINAL
Tubulointerstitial nephritis antigen-like

1

0

High-throughput

0.513

High

224519

XYLT2
Xylosyltransferase 2

1

0

High-throughput

0.513

High

224521

TOR3A
Torsin-3A

1

0

High-throughput

0.513

High

224531

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.513

High

136576

MANBA
Beta-mannosidase

1

1

High-throughput

0.489

High

224453

LRP5
Low-density lipoprotein receptor-related protein 5

1

5

High-throughput

0.489

High

224454

LRP6
Low-density lipoprotein receptor-related protein 6

1

5

High-throughput

0.489

High

224455

GLSK
Glutaminase kidney isoform, mitochondrial

1

1

High-throughput

0.489

High

224456

TRI37
E3 ubiquitin-protein ligase TRIM37

1

1

High-throughput

0.489

High

224459

LDLR
Low-density lipoprotein receptor

1

5

High-throughput

0.489

High

224465

FGFR4
Fibroblast growth factor receptor 4

1

1

High-throughput

0.489

High

224466

FGFR3
Fibroblast growth factor receptor 3

1

1

High-throughput

0.489

High

224471

CDK7
Cyclin-dependent kinase 7

1

1

High-throughput

0.489

High

224480

SEM3B
Semaphorin-3B

1

2

High-throughput

0.489

High

224482

LAMB3
Laminin subunit beta-3

1

7

High-throughput

0.489

High

224488

EOGT
EGF domain-specific O-linked N-acetylglucosamine transferase

1

2

High-throughput

0.489

High

224491

GLT18
Polypeptide N-acetylgalactosaminyltransferase 18

1

2

High-throughput

0.489

High

224493

ARSK
Arylsulfatase K

1

3

High-throughput

0.489

High

224497

GLT10
Polypeptide N-acetylgalactosaminyltransferase 10

1

2

High-throughput

0.489

High

224499

P3H3
Prolyl 3-hydroxylase 3

1

2

High-throughput

0.489

High

224501

GLT12
Polypeptide N-acetylgalactosaminyltransferase 12

1

2

High-throughput

0.489

High

224509

SC65
Endoplasmic reticulum protein SC65

1

2

High-throughput

0.489

High

224514

I17RA
Interleukin-17 receptor A

1

1

High-throughput

0.489

High

224523

CHPF2
Chondroitin sulfate glucuronyltransferase

1

1

High-throughput

0.489

High

224528

ATS7
A disintegrin and metalloproteinase with thrombospondin motifs 7

1

3

High-throughput

0.489

High

224458

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.437

High

224467

CCN2
CCN family member 2

1

0

High-throughput

0.426

High

224502

K319L
Dyslexia-associated protein KIAA0319-like protein

2

0

High-throughput

0.313

High

76081

B4DET5
cDNA FLJ59484, highly similar to Nuclear envelope pore membrane protein POM 121

1

0

High-throughput

0.279

Low

224457

DYR
Dihydrofolate reductase

1

0

High-throughput

0.279

Low

224460

DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain

1

0

High-throughput

0.279

Low

224470

NMU
Neuromedin-U [Cleaved into: Neuromedin precursor-related peptide 36

1

0

High-throughput

0.279

Low

224474

CCNH
Cyclin-H

1

0

High-throughput

0.279

Low

224475

MAT1
CDK-activating kinase assembly factor MAT1

1

0

High-throughput

0.279

Low

224481

MTMR1
Phosphatidylinositol-3-phosphate phosphatase MTMR1

1

0

High-throughput

0.279

Low

224484

ALG11
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase

1

0

High-throughput

0.279

Low

224485

RA1L2
Heterogeneous nuclear ribonucleoprotein A1-like 2

1

0

High-throughput

0.279

Low

224486

OFUT4
GDP-fucose protein O-fucosyltransferase 4

1

0

High-throughput

0.279

Low

224489

GT253
Inactive glycosyltransferase 25 family member 3

1

0

High-throughput

0.279

Low

224495

SPT6H
Transcription elongation factor SPT6

1

0

High-throughput

0.279

Low

224500

FXRD2
FAD-dependent oxidoreductase domain-containing protein 2

1

0

High-throughput

0.279

Low

224503

SUMF1
Formylglycine-generating enzyme

1

0

High-throughput

0.279

Low

224504

PGLT1
Protein O-glucosyltransferase 1

1

0

High-throughput

0.279

Low

224508

PTPRU
Receptor-type tyrosine-protein phosphatase U

1

0

High-throughput

0.279

Low

224512

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

0

High-throughput

0.279

Low

224513

MIB2
E3 ubiquitin-protein ligase MIB2

1

0

High-throughput

0.279

Low

224517

EDEM3
ER degradation-enhancing alpha-mannosidase-like protein 3

1

0

High-throughput

0.279

Low

224522

UGGG2
UDP-glucose:glycoprotein glucosyltransferase 2

1

0

High-throughput

0.279

Low

224524

SUN2
SUN domain-containing protein 2

1

0

High-throughput

0.279

Low

224525

MRM2
rRNA methyltransferase 2, mitochondrial

1

0

High-throughput

0.279

Low

224530

SBDS
Ribosome maturation protein SBDS

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025