Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1
Interactor 2: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.985 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25852190, 31980649, 8702721, 7644510, 35271311, 32707033, 36244648, 38496616, 16041367, 36931259, 11697890, 17979178, 16093354, 19608861, unassigned2173, 37045861 |
| Identification Methods | affinity chromatography technology, two hybrid, proximity labelling technology, anti tag coimmunoprecipitation, pull down, cross-linking study, biochemical |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | 14-3-3~C1_1 |
| Common GO terms | GO:0000165 - MAPK cascade GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction and 1 others more... |
| Homologous interactions | 12 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Gg | |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
| + | At | |
|
|||||||||||
| + | At | |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | At | |
|
|||||||||||
| + | Hs |  |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
