HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: TBA4A (P68366)
Tubulin alpha-4A chain (EC 3.6.5.-) (Alpha-tubulin 1) (Testis-specific alpha-tubulin) (Tubulin H2-alpha) (Tubulin alpha-1 chain)
Gene: TUBA4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0046872 - metal ion binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 448
+	Hs
		373536 RAF1_HUMAN (1-648): 0: 652: 100.00		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Hs
		374034 RAF1_HUMAN (1-648): 0: 652: 100.00		TBB4B_HUMAN (1-437): 0: 695: 40.28
+	Hs
		374985 RAF1_HUMAN (1-648): 0: 652: 100.00		TBA8_HUMAN (1-440): 0: 691: 90.23
+	Hs
		488671 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		TBA4A_HUMAN (1-448): 0: 724: 100.00
+	Hs
		488750 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	Hs
		427981 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Hs
		488672 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		TBB4B_HUMAN (1-437): 0: 695: 40.28
+	Hs
		522895 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		TBA4A_HUMAN (1-448): 0: 724: 100.00
+	Hs
		522894 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		TBA1B_HUMAN (1-439): 0: 715: 97.49
+	Hs
		427991 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Zm
		41793 A0A1D6NRI5_MAIZE (315-633): 4.57e-40: 159: 30.81		A0A1R3MJR2_MAIZE (1-438): 0: 688: 83.33