HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: PABP2 (Q86U42)
Polyadenylate-binding protein 2 (PABP-2) (Poly(A)-binding protein 2) (Nuclear poly(A)-binding protein 1) (Poly(A)-binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1)
Gene: PABPN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36244648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0000165 - MAPK cascade GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 306
+	Hs
		373836 RAF1_HUMAN (1-648): 0: 652: 100.00		RBM34_HUMAN (117-251): 1.51e-30: 121: 31.11
+	Hs
		373915 RAF1_HUMAN (1-648): 0: 652: 100.00		NCBP2_HUMAN (142-298): 5.3e-33: 120: 15.82
+	Hs
		374053 RAF1_HUMAN (1-648): 0: 652: 100.00		RBM3_HUMAN (167-304): 1.15e-32: 119: 22.45
+	Hs
		374212 RAF1_HUMAN (1-648): 0: 652: 100.00		CIRBP_HUMAN (167-306): 3.86e-32: 119: 19.15
+	Hs
		373604 RAF1_HUMAN (1-648): 0: 652: 100.00		PABP1_HUMAN (59-260): 3.2e-22: 98.8: 11.33
+	Hs
		374678 RAF1_HUMAN (1-648): 0: 652: 100.00		DAZP1_HUMAN (163-285): 3.6e-21: 94.6: 21.14
+	Hs
		374171 RAF1_HUMAN (1-648): 0: 652: 100.00		PABP4_HUMAN (163-260): 1.04e-20: 94.2: 17.17
+	Hs
		488712 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		CIRBP_HUMAN (167-306): 3.86e-32: 119: 19.15
+	Hs
		488548 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		PABP1_HUMAN (59-260): 3.2e-22: 98.8: 11.33
+	Hs
		488705 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		PABP4_HUMAN (163-260): 1.04e-20: 94.2: 17.17
+	Hs
		516342 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP1_HUMAN (59-260): 3.2e-22: 98.8: 11.33
+	Hs
		522960 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP4_HUMAN (163-260): 1.04e-20: 94.2: 17.17
+	Hs
		523147 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		PABP3_HUMAN (59-260): 1.51e-19: 90.7: 11.82