HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: C170B (Q9Y4F5)
Centrosomal protein of 170 kDa protein B (Centrosomal protein 170B) (Cep170B)
Gene: CEP170B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 1589
+	Hs
		376137 RASK_HUMAN (1-188): 1.61e-84: 249: 86.24		C170B_HUMAN (1-1589): 0: 645: 100.00
+	Hs
		319042 RASN_HUMAN (1-188): 4.47e-88: 257: 85.64		K0754_HUMAN (815-1579): 1.74e-13: 78.5: 10.85
+	Hs
		319043 RASK_HUMAN (1-188): 1.61e-84: 249: 86.24		K0754_HUMAN (815-1579): 1.74e-13: 78.5: 10.85
+	Hs
		376106 RASK_HUMAN (1-188): 1.61e-84: 249: 86.24		SRRM2_HUMAN (789-1567): 3.19e-12: 74.1: 9.50
+	Hs
		375418 RASK_HUMAN (1-188): 1.61e-84: 249: 86.24		ANK2_HUMAN (227-1139): 8.89e-12: 72.8: 12.69
+	Hs
		375784 RASK_HUMAN (1-188): 1.61e-84: 249: 86.24		TITIN_HUMAN (143-1056): 9.55e-11: 69.5: 9.50
+	Hs
		374532 RASH_HUMAN (16-189): 6.27e-73: 219: 100.00		ANK2_HUMAN (227-1139): 8.89e-12: 72.8: 12.69
+	Hs
		976456 RB11A_HUMAN (4-178): 6.31e-73: 220: 33.90		TITIN_HUMAN (143-1056): 9.55e-11: 69.5: 9.50
+	Hs
		957965 RAB14_HUMAN (4-180): 2.65e-71: 216: 29.05		CRBG2_HUMAN (382-1320): 2.28e-11: 71.2: 12.46
+	Hs
		957983 RAB14_HUMAN (4-180): 2.65e-71: 216: 29.05		TITIN_HUMAN (143-1056): 9.55e-11: 69.5: 9.50
+	Dm
		68588 RALA_DROME (4-167): 1.35e-61: 191: 55.15		A8JNM5_DROME (328-1292): 3.93e-11: 70.5: 12.46