HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: LRRF2 (Q9Y608)
Leucine-rich repeat flightless-interacting protein 2 (LRR FLII-interacting protein 2)
Gene: LRRFIP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	36244648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 721
+	Hs
		374316 RAF1_HUMAN (1-648): 0: 652: 100.00		LRRF1_HUMAN (280-458): 7.43e-52: 195: 56.35
+	Hs
		374373 RAF1_HUMAN (1-648): 0: 652: 100.00		MRCKA_HUMAN (231-721): 3.54e-31: 133: 11.66
+	Hs
		375162 RAF1_HUMAN (1-648): 0: 652: 100.00		MRCKB_HUMAN (402-721): 6.25e-17: 87.6: 15.27
+	Hs
		373794 RAF1_HUMAN (1-648): 0: 652: 100.00		MYH11_HUMAN (421-721): 1.67e-13: 76.8: 16.56
+	Hs
		374582 RAF1_HUMAN (1-648): 0: 652: 100.00		DLG5_HUMAN (219-569): 1.09e-12: 74.1: 10.72
+	Hs
		373791 RAF1_HUMAN (1-648): 0: 652: 100.00		MYH10_HUMAN (466-719): 8.82e-11: 67.9: 16.93
+	Hs
		375074 RAF1_HUMAN (1-648): 0: 652: 100.00		MYH13_HUMAN (205-636): 4.94e-10: 65.2: 8.28
+	Hs
		373790 RAF1_HUMAN (1-648): 0: 652: 100.00		MYH9_HUMAN (417-721): 2.86e-09: 62.9: 13.12
+	Hs
		488765 ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28		MY18A_HUMAN (332-715): 3.36e-12: 72.4: 11.16
+	Hs
		523231 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		MYH4_HUMAN (219-656): 1.68e-11: 70.3: 11.38
+	Hs
		412287 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		MY18A_HUMAN (332-715): 3.36e-12: 72.4: 11.16
+	Hs
		111443 J3QRU1_HUMAN (329-607): 1.4e-105: 332: 33.92		MYH9_HUMAN (417-721): 2.86e-09: 62.9: 13.12
+	Hs
		433272 YES_HUMAN (329-607): 1.22e-105: 332: 33.92		MYH9_HUMAN (417-721): 2.86e-09: 62.9: 13.12
+	Hs
		412058 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		MYH9_HUMAN (417-721): 2.86e-09: 62.9: 13.12