Protein: PSB3
Proteasome subunit beta type-3 (Proteasome chain 13) (Proteasome component C10-II) (Proteasome theta chain)

Gene: PSB3, PSMB3
Organism: Homo sapiens
Interactions: 181
UniProt ID: P49720

Gene Ontology (top 5):
GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

831958

PSB2
Proteasome subunit beta type-2

7

20

Small-scale

0.967

High

832032

PSB7
Proteasome subunit beta type-7

7

19

Small-scale

0.967

High

637648

PSA2
Proteasome subunit alpha type-2

6

19

Small-scale

0.955

High

594478

PSB1
Proteasome subunit beta type-1

6

20

Small-scale

0.953

High

832060

POMP
Proteasome maturation protein

6

12

Small-scale

0.949

High

656680

PSB5
Proteasome subunit beta type-5

6

19

Small-scale

0.949

High

637359

PSA1
Proteasome subunit alpha type-1

5

20

High-throughput

0.922

High

771441

PSB10
Proteasome subunit beta type-10

5

20

Small-scale

0.922

High

156251

PSA7
Proteasome subunit alpha type-7

4

20

Small-scale

0.908

High

656098

PSB9
Proteasome subunit beta type-9

4

20

High-throughput

0.903

High

656429

PSB4
Proteasome subunit beta type-4

4

19

Small-scale

0.897

High

121707

PSD11
26S proteasome non-ATPase regulatory subunit 11

3

20

High-throughput

0.871

High

730214

PRS7
26S proteasome regulatory subunit 7

3

20

High-throughput

0.871

High

831971

PRS4
26S proteasome regulatory subunit 4

3

20

High-throughput

0.871

High

831972

PRS8
26S proteasome regulatory subunit 8

3

20

High-throughput

0.871

High

831973

PRS10
26S proteasome regulatory subunit 10B

3

20

High-throughput

0.871

High

831980

PSME1
Proteasome activator complex subunit 1

3

20

High-throughput

0.871

High

831991

PSME4
Proteasome activator complex subunit 4

3

11

High-throughput

0.871

High

656569

PSB6
Proteasome subunit beta type-6

3

18

Small-scale

0.863

High

572894

PRS6A
26S proteasome regulatory subunit 6A

3

20

High-throughput

0.861

High

638085

PSA4
Proteasome subunit alpha type-4

3

20

High-throughput

0.861

High

831968

PSA6
Proteasome subunit alpha type-6

3

20

Small-scale

0.855

High

637811

PSA3
Proteasome subunit alpha type-3

2

20

High-throughput

0.811

High

656173

PSA5
Proteasome subunit alpha type-5

2

20

High-throughput

0.811

High

798613

PRS6B
26S proteasome regulatory subunit 6B

2

20

High-throughput

0.811

High

831970

PSME3
Proteasome activator complex subunit 3

2

20

High-throughput

0.811

High

832023

PSMA8
Proteasome subunit alpha-type 8

2

20

High-throughput

0.811

High

832056

PSME2
Proteasome activator complex subunit 2

2

20

High-throughput

0.811

High

656046

PSB8
Proteasome subunit beta type-8

2

20

Small-scale

0.793

High

831957

PSB3
Proteasome subunit beta type-3

2

19

Small-scale

0.767

High

130797

PSDE
26S proteasome non-ATPase regulatory subunit 14

6

20

Small-scale

0.730

High

832068

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

5

16

Small-scale

0.714

High

831993

PSMD6
26S proteasome non-ATPase regulatory subunit 6

4

20

High-throughput

0.699

High

832063

FBX7
F-box only protein 7

4

6

Small-scale

0.694

High

536758

TRI27
Zinc finger protein RFP

3

2

High-throughput

0.675

High

198575

PSMD3
26S proteasome non-ATPase regulatory subunit 3

3

10

High-throughput

0.675

High

314745

PSMG1
Proteasome assembly chaperone 1

3

5

High-throughput

0.675

High

832038

PIP30
PSME3-interacting protein

3

3

High-throughput

0.675

High

832059

PSD13
26S proteasome non-ATPase regulatory subunit 13

3

14

High-throughput

0.675

High

831965

PSMD4
26S proteasome non-ATPase regulatory subunit 4

3

12

High-throughput

0.667

High

832001

AKIR2
Akirin-2

3

10

Small-scale

0.667

High

832033

PSMD1
26S proteasome non-ATPase regulatory subunit 1

3

20

High-throughput

0.667

High

831979

UBE3A
Ubiquitin-protein ligase E3A

3

14

Small-scale

0.640

High

121966

PSD12
26S proteasome non-ATPase regulatory subunit 12

2

20

High-throughput

0.628

High

819777

PSMD8
26S proteasome non-ATPase regulatory subunit 8

2

9

High-throughput

0.628

High

831960

PSMD7
26S proteasome non-ATPase regulatory subunit 7

2

20

High-throughput

0.628

High

831983

PSMD2
26S proteasome non-ATPase regulatory subunit 2

2

20

High-throughput

0.628

High

832026

PSMF1
Proteasome inhibitor PI31 subunit

2

4

High-throughput

0.628

High

832028

PSMG2
Proteasome assembly chaperone 2

2

11

High-throughput

0.628

High

832049

RN181
E3 ubiquitin-protein ligase RNF181

2

7

High-throughput

0.628

High

832035

PSMG3
Proteasome assembly chaperone 3

3

5

Small-scale

0.612

High

346233

MYC
Myc proto-oncogene protein

2

5

High-throughput

0.611

High

528772

CFTR
Cystic fibrosis transmembrane conductance regulator

2

7

High-throughput

0.611

High

132780

SDCB1
Syntenin-1

2

2

High-throughput

0.606

High

832010

Q6IBT1
Proteasome subunit beta

1

20

High-throughput

0.590

High

226855

PRKN
E3 ubiquitin-protein ligase parkin

2

20

Small-scale

0.584

High

92610

E9PMD8
Proteasome 26S subunit, ATPase 3

1

20

High-throughput

0.575

High

108933

H0YKT8
Proteasome subunit beta

1

20

High-throughput

0.575

High

832003

PSMG4
Proteasome assembly chaperone 4

2

3

High-throughput

0.574

High

832048

OSER1
Oxidative stress-responsive serine-rich protein 1

2

1

High-throughput

0.574

High

832004

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

5

High-throughput

0.571

High

831966

ANM2
Protein arginine N-methyltransferase 2

1

1

High-throughput

0.541

High

362943

FINC
Fibronectin

1

4

High-throughput

0.536

High

508874

TOP2A
DNA topoisomerase 2-alpha

1

3

High-throughput

0.536

High

831974

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

16

High-throughput

0.536

High

831976

SKP1
S-phase kinase-associated protein 1

1

9

High-throughput

0.536

High

831981

TRAF2
TNF receptor-associated factor 2

1

9

High-throughput

0.536

High

831984

CUL1
Cullin-1

1

7

High-throughput

0.536

High

831994

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

11

High-throughput

0.536

High

831995

UBE3C
Ubiquitin-protein ligase E3C

1

19

High-throughput

0.536

High

832002

PDZ11
PDZ domain-containing protein 11

1

2

High-throughput

0.536

High

832006

ECM29
Proteasome adapter and scaffold protein ECM29

1

11

High-throughput

0.536

High

832014

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

20

High-throughput

0.536

High

832021

ARRD4
Arrestin domain-containing protein 4

1

9

High-throughput

0.536

High

832034

SLX1
Structure-specific endonuclease subunit SLX1

1

4

High-throughput

0.536

High

832043

AKIR1
Akirin-1

1

10

High-throughput

0.536

High

832055

AMFR
E3 ubiquitin-protein ligase AMFR

1

12

High-throughput

0.536

High

832064

LMBL1
Lethal(3)malignant brain tumor-like protein 1

1

7

High-throughput

0.536

High

771832

VHL
von Hippel-Lindau disease tumor suppressor

1

3

High-throughput

0.515

High

832012

DUSTY
Dual serine/threonine and tyrosine protein kinase

1

3

High-throughput

0.515

High

791379

HD
Huntingtin

1

4

High-throughput

0.515

High

555350

H2AX
Histone H2AX

1

0

High-throughput

0.513

High

831992

CND2
Condensin complex subunit 2

1

0

High-throughput

0.513

High

832019

FANCB
Fanconi anemia group B protein

1

0

High-throughput

0.513

High

832031

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

0

High-throughput

0.513

High

832061

HPSE
Heparanase

1

0

High-throughput

0.513

High

171485

UBD
Ubiquitin D

1

20

Small-scale

0.501

High

386313

P53
Cellular tumor antigen p53

1

1

Small-scale

0.501

High

316824

KLF8
Krueppel-like factor 8

1

17

High-throughput

0.500

High

832036

KLF16
Krueppel-like factor 16

1

17

High-throughput

0.500

High

832054

KLF15
Krueppel-like factor 15

1

17

High-throughput

0.500

High

832047

FANCL
E3 ubiquitin-protein ligase FANCL

1

0

High-throughput

0.493

High

506295

MBL2
Mannose-binding protein C

1

2

High-throughput

0.489

High

832008

NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1

1

2

High-throughput

0.489

High

832066

TGRM1
TOG array regulator of axonemal microtubules protein 1

1

1

High-throughput

0.489

High

160446

AURKA
Aurora kinase A

1

8

High-throughput

0.479

High

214144

SPOP
Speckle-type POZ protein

1

2

High-throughput

0.479

High

244114

BRD4
Bromodomain-containing protein 4

1

5

High-throughput

0.479

High

255592

OBSL1
Obscurin-like protein 1

1

6

High-throughput

0.479

High

294532

RECQ4
ATP-dependent DNA helicase Q4

1

6

High-throughput

0.479

High

303019

HEXI1
Protein HEXIM1

1

4

High-throughput

0.479

High

304803

MFN2
Mitofusin-2

1

5

High-throughput

0.479

High

324277

BAG3
BAG family molecular chaperone regulator 3

1

5

High-throughput

0.479

High

354365

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

3

High-throughput

0.479

High

397841

ISG15
Ubiquitin-like protein ISG15

1

20

Small-scale

0.479

High

441712

CFAH
Complement factor H

1

1

Small-scale

0.479

High

487230

ANDR
Androgen receptor

1

7

High-throughput

0.479

High

505586

EPB41
Protein 4.1

1

2

High-throughput

0.479

High

552225

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

570499

PTN2
Tyrosine-protein phosphatase non-receptor type 2

1

5

High-throughput

0.479

High

650664

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

719962

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.479

High

817792

SOX2
Transcription factor SOX-2

1

3

High-throughput

0.479

High

831959

MCM2
DNA replication licensing factor MCM2

1

3

High-throughput

0.479

High

831961

PLK1
Serine/threonine-protein kinase PLK1

1

17

Small-scale

0.479

High

831962

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

10

High-throughput

0.479

High

831963

RD23A
UV excision repair protein RAD23 homolog A

1

20

Small-scale

0.479

High

831964

RD23B
UV excision repair protein RAD23 homolog B

1

20

High-throughput

0.479

High

831967

IF6
Eukaryotic translation initiation factor 6

1

1

High-throughput

0.479

High

831969

ABCE1
ATP-binding cassette sub-family E member 1

1

2

High-throughput

0.479

High

831975

1433Z
14-3-3 protein zeta/delta

1

2

High-throughput

0.479

High

831977

H31
Histone H3.1

1

1

High-throughput

0.479

High

831982

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

1

Small-scale

0.479

High

831985

CUL4A
Cullin-4A

1

7

High-throughput

0.479

High

831986

DX39B
Spliceosome RNA helicase DDX39B

1

2

High-throughput

0.479

High

831987

TRI14
Tripartite motif-containing protein 14

1

10

High-throughput

0.479

High

831988

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

6

High-throughput

0.479

High

831989

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

5

Small-scale

0.479

High

831990

RBM39
RNA-binding protein 39

1

5

High-throughput

0.479

High

831996

ADRM1
Proteasomal ubiquitin receptor ADRM1

1

9

High-throughput

0.479

High

831997

MK06
Mitogen-activated protein kinase 6

1

5

High-throughput

0.479

High

831998

CL16A
Protein CLEC16A

1

4

High-throughput

0.479

High

831999

LARP7
La-related protein 7

1

4

High-throughput

0.479

High

832000

MIDN
Midnolin

1

5

High-throughput

0.479

High

832005

DDI2
Protein DDI1 homolog 2

1

20

High-throughput

0.479

High

832009

VIR
Protein virilizer homolog

1

5

High-throughput

0.479

High

832011

DESI1
Desumoylating isopeptidase 1

1

4

Small-scale

0.479

High

832013

TRI67
Tripartite motif-containing protein 67

1

18

High-throughput

0.479

High

832016

GOLI
E3 ubiquitin-protein ligase RNF130

1

19

High-throughput

0.479

High

832017

RPTOR
Regulatory-associated protein of mTOR

1

2

High-throughput

0.479

High

832022

NUP35
Nucleoporin NUP35

1

2

High-throughput

0.479

High

832027

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

16

High-throughput

0.479

High

832029

DDRGK
DDRGK domain-containing protein 1

1

3

High-throughput

0.479

High

832030

RITA1
RBPJ-interacting and tubulin-associated protein 1

1

6

Small-scale

0.479

High

832037

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

5

Small-scale

0.479

High

832039

SPRTN
DNA-dependent metalloprotease SPRTN

1

2

High-throughput

0.479

High

832041

PKHA4
Pleckstrin homology domain-containing family A member 4

1

5

High-throughput

0.479

High

832042

RMD5A
E3 ubiquitin-protein transferase RMND5A

1

1

High-throughput

0.479

High

832044

UNKL
Putative E3 ubiquitin-protein ligase UNKL

1

4

High-throughput

0.479

High

832046

UBQL4
Ubiquilin-4

1

20

Small-scale

0.479

High

832050

HECW2
E3 ubiquitin-protein ligase HECW2

1

7

High-throughput

0.479

High

832051

TRM7
tRNA

1

2

High-throughput

0.479

High

832052

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

832053

UBQL2
Ubiquilin-2

1

20

High-throughput

0.479

High

832057

FZR1
Fizzy-related protein homolog

1

8

High-throughput

0.479

High

832058

UBQL1
Ubiquilin-1

1

20

High-throughput

0.479

High

832067

TRAF6
TNF receptor-associated factor 6

1

9

High-throughput

0.479

High

617480

CRCM
Colorectal mutant cancer protein

1

0

High-throughput

0.458

High

832015

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

832040

SHRPN
Sharpin

1

0

Small-scale

0.458

High

832045

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

0

High-throughput

0.458

High

832062

DTX4
E3 ubiquitin-protein ligase DTX4

1

0

Small-scale

0.458

High

832065

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

0

High-throughput

0.458

High

694

A0A087WW66
26S proteasome non-ATPase regulatory subunit 1

1

20

High-throughput

0.445

High

401640

JUN
Transcription factor Jun

1

10

High-throughput

0.445

High

496564

TAU
Microtubule-associated protein tau

1

5

High-throughput

0.445

High

100593

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

239530

EIF1B
Eukaryotic translation initiation factor 1b

1

1

High-throughput

0.437

High

329498

AGR2
Anterior gradient protein 2 homolog

1

5

High-throughput

0.437

High

832007

DCA15
DDB1- and CUL4-associated factor 15

1

1

High-throughput

0.437

High

832024

DPTOR
DEP domain-containing mTOR-interacting protein

1

2

Small-scale

0.437

High

832025

DDI1
Protein DDI1 homolog 1

1

20

High-throughput

0.437

High

832069

INSI2
Insulin-induced gene 2 protein

1

2

Small-scale

0.437

High

831098

CEBPA
CCAAT/enhancer-binding protein alpha

1

7

High-throughput

0.408

High

832020

MOT11
Monocarboxylate transporter 11

1

5

High-throughput

0.407

High

832018

EFC4A
EF-hand calcium-binding domain-containing protein 4A

2

0

High-throughput

0.316

High

627177

MYP0
Myelin protein P0

1

0

High-throughput

0.282

High

831978

HTRA4
Serine protease HTRA4

1

0

High-throughput

0.279

Low

351732

SOMA
Somatotropin

1

0

High-throughput

0.249

Low

572598

VGFR1
Vascular endothelial growth factor receptor 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024