Interactor 1: GUAA (P04079)
GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) (GMP synthetase) (GMPS) (Glutamine amidotransferase)
Gene: GUAA

Interactor 2: GUAA (P04079)
GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) (GMP synthetase) (GMPS) (Glutamine amidotransferase)
Gene: GUAA

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.834

The method score is based on:

Property Details
Experiments 8548458, unassigned104, 16858726
Identification Methods x-ray crystallography, comigration in non denaturing gel electrophoresis, blue native page
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains GATase~GATase, GATase~GMP_synt_C, GATase~NAD_synthase, GMP_synt_C~GMP_synt_C, GMP_synt_C~NAD_synthase, NAD_synthase~NAD_synthase
Common GO terms GO:0003921 - GMP synthase activity
GO:0003922 - GMP synthase (glutamine-hydrolyzing) activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006177 - GMP biosynthetic process
and 1 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 525
Ec

1 525
+ Hs
+ Sc
+ Ec
+ Pf
+ Ec

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Last updated: 15 Jul 2024