HitPredict

Interactor 1: CYTB (P04080)
Cystatin-B (CPI-B) (Liver thiol proteinase inhibitor) (Stefin-B)
Gene: CSTB

Interactor 2: CATH (P09668)
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H (EC 3.4.22.16); Cathepsin H heavy chain; Cathepsin H light chain]
Gene: CTSH

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.799

The method score is based on:

Property Details
Experiments 11514663, 33961781
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cystatin~Peptidase_C1
Common GO terms GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005829 - cytosol
GO:0034774 - secretory granule lumen
GO:0062023 - collagen-containing extracellular matrix
and 3 others

more...
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 98
Hs

1 335
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024