HitPredict

Interactor 1: PABP (P04147)
Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (ARS consensus-binding protein ACBP-67) (Polyadenylate tail-binding protein)
Gene: PAB1

Interactor 2: PAN2 (P53010)
PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (EC 3.1.13.4) (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 2) (PAN deadenylation complex subunit 2)
Gene: PAN2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.660

Property	Details
Experiments	16429126, 31104843, 37968396
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0006397 - mRNA processing
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 577 Sc			1 1115
+	Hs
		1031353 PABP4_HUMAN (3-218): 3.47e-31: 130: 24.79		PAN2_HUMAN (31-1111): 0: 804: 24.13
+	Hs
		582323 NUCL_HUMAN (219-418): 4.27e-23: 105: 20.00		PAN2_HUMAN (31-1111): 0: 804: 24.13
+	Hs
		516542 PABP1_HUMAN (312-407): 8.73e-15: 79.5: 28.87		PAN2_HUMAN (31-1111): 0: 804: 24.13
+	Hs
		1031331 PABP4_HUMAN (3-218): 3.47e-31: 130: 24.79		UBP10_HUMAN (302-856): 7.88e-74: 263: 12.65
+	Hs
		582533 NUCL_HUMAN (219-418): 4.27e-23: 105: 20.00		UBP36_HUMAN (450-938): 1.46e-73: 267: 13.53
+	Hs
		516747 PABP1_HUMAN (312-407): 8.73e-15: 79.5: 28.87		UBP22_HUMAN (466-856): 2.83e-80: 274: 11.99
+	Hs
		516521 PABP1_HUMAN (312-407): 8.73e-15: 79.5: 28.87		UBP10_HUMAN (302-856): 7.88e-74: 263: 12.65
+	Hs
		1220120 PABP5_HUMAN (1-120): 1.45e-16: 83.7: 14.05		GOR_HUMAN (920-1088): 9.78e-45: 175: 22.41