Protein: GDF9
Growth/differentiation factor 9 (GDF-9)

Gene: GDF9
Organism: Homo sapiens
Interactions: 58
UniProt ID: O60383

Gene Ontology (top 5):
GO:0001555 - oocyte growth
GO:0005125 - cytokine activity
GO:0005615 - extracellular space
GO:0005737 - cytoplasm
GO:0007179 - transforming growth factor beta receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

248406

VWA1
von Willebrand factor A domain-containing protein 1

1

0

High-throughput

0.656

High

248397

BMPR2
Bone morphogenetic protein receptor type-2

1

20

Small-scale

0.647

High

248393

TBA4A
Tubulin alpha-4A chain

2

2

High-throughput

0.628

High

248402

TBB8
Tubulin beta-8 chain

2

2

High-throughput

0.628

High

248403

ACTBL
Beta-actin-like protein 2

2

2

High-throughput

0.628

High

248422

FBX2
F-box only protein 2

2

7

High-throughput

0.628

High

248382

MYH11
Myosin-11

2

0

High-throughput

0.602

High

248400

SMN
Survival motor neuron protein

2

0

High-throughput

0.594

High

248374

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

2

High-throughput

0.541

High

248377

S10A8
Protein S100-A8

1

3

High-throughput

0.541

High

248378

TDGF1
Protein Cripto

1

11

High-throughput

0.541

High

248384

CDN2C
Cyclin-dependent kinase 4 inhibitor C

1

2

High-throughput

0.541

High

248385

SPB9
Serpin B9

1

8

High-throughput

0.541

High

248395

ILF3
Interleukin enhancer-binding factor 3

1

2

High-throughput

0.541

High

248398

KIF22
Kinesin-like protein KIF22

1

1

High-throughput

0.541

High

248420

STRN4
Striatin-4

1

3

High-throughput

0.541

High

248392

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

3

High-throughput

0.536

High

248394

PGBM
Basement membrane-specific heparan sulfate proteoglycan core protein

1

4

High-throughput

0.536

High

248396

TBB3
Tubulin beta-3 chain

1

2

High-throughput

0.536

High

248399

PA1B3
Platelet-activating factor acetylhydrolase IB subunit alpha1

1

0

High-throughput

0.518

High

248409

RSRC1
Serine/Arginine-related protein 53

1

0

High-throughput

0.518

High

248412

MYCBP
c-Myc-binding protein

1

0

High-throughput

0.518

High

248424

PHOCN
MOB-like protein phocein

1

0

High-throughput

0.518

High

126928

APBB1
Amyloid beta precursor protein binding family B member 1

1

0

High-throughput

0.513

High

248380

ANXA7
Annexin A7

1

1

High-throughput

0.508

High

246323

KDM1A
Lysine-specific histone demethylase 1A

1

1

High-throughput

0.494

High

248389

FOXG1
Forkhead box protein G1

1

1

High-throughput

0.494

High

248408

CREL1
Protein disulfide isomerase CRELD1

1

10

High-throughput

0.494

High

248410

TRIB3
Tribbles homolog 3

1

2

High-throughput

0.494

High

248416

BTBD2
BTB/POZ domain-containing protein 2

1

1

High-throughput

0.494

High

248423

PCDA4
Protocadherin alpha-4

1

3

High-throughput

0.494

High

248407

VWDE
von Willebrand factor D and EGF domain-containing protein

1

8

High-throughput

0.489

High

248426

PCDG6
Protocadherin gamma-A6

1

3

High-throughput

0.489

High

248375

GA45G
Growth arrest and DNA damage-inducible protein GADD45 gamma

1

0

High-throughput

0.486

High

248383

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.486

High

248386

DYN2
Dynamin-2

1

0

High-throughput

0.486

High

248413

PCY2
Ethanolamine-phosphate cytidylyltransferase

1

0

High-throughput

0.486

High

248379

H15
Histone H1.5

1

2

High-throughput

0.470

High

248388

APLP1
Amyloid beta precursor like protein 1

1

5

High-throughput

0.439

High

248421

NSMA2
Sphingomyelin phosphodiesterase 3

1

0

High-throughput

0.438

High

248401

AP5B1
AP-5 complex subunit beta-1

2

0

High-throughput

0.328

High

248376

KITH
Thymidine kinase, cytosolic

2

0

High-throughput

0.323

High

127836

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

0

High-throughput

0.282

High

248381

SAT1
Diamine acetyltransferase 1

1

0

High-throughput

0.282

High

248387

RB27A
Ras-related protein Rab-27A

1

0

High-throughput

0.282

High

248390

RUXG
Small nuclear ribonucleoprotein G

1

0

High-throughput

0.282

High

248391

LSM3
U6 snRNA-associated Sm-like protein LSm3

1

0

High-throughput

0.282

High

248405

PMF1
Polyamine-modulated factor 1

1

0

High-throughput

0.282

High

248411

ORAI2
Protein orai-2

1

0

High-throughput

0.282

High

248414

MPH6
M-phase phosphoprotein 6

1

0

High-throughput

0.282

High

248417

FXYD6
FXYD domain-containing ion transport regulator 6

1

0

High-throughput

0.282

High

248425

WASC3
WASH complex subunit 3

1

0

High-throughput

0.282

High

248427

NDUB9
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9

1

0

High-throughput

0.282

High

248404

ZN691
Zinc finger protein 691

1

0

High-throughput

0.279

Low

248418

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.279

Low

248419

ANLN
Anillin

1

0

High-throughput

0.249

Low

211672

LEU1
Leukemia-associated protein 1

1

0

High-throughput

0.238

Low

248415

ADPGK
ADP-dependent glucokinase

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025