HitPredict

Interactor 1: GCR (P04150)
Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1)
Gene: NR3C1

Interactor 2: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.766

The method score is based on:

Property Details
Experiments 24462205, 16131566, 26804907, 8139547, 28537252, 10903152, 12093808, 9334248, 15916966, 9195923, 8089152, 19875381, 14987994, 27803151, 15004035, 8898375, 8645634, 8621522, 35124280, 34610959 and 3 others

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Identification Methods affinity chromatography technology, pull down, protein complementation assay, coimmunoprecipitation, mammalian protein protein interaction trap, display technology
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 2 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 777
Hs

1 732
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024