Protein: ERD22
ER lumen protein-retaining receptor 2 (ERD2-like protein 1) (ELP-1) (KDEL endoplasmic reticulum protein retention receptor 2) (KDEL receptor 2)

Gene: ERD22, KDELR2
Organism: Homo sapiens
Interactions: 101
UniProt ID: P33947

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005046 - KDEL sequence binding
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005801 - cis-Golgi network

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

383645

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

3

High-throughput

0.585

High

484263

VSIG8
V-set and immunoglobulin domain-containing protein 8

1

1

High-throughput

0.575

High

49403

TMM72
Transmembrane protein 72

1

1

High-throughput

0.536

High

505348

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

2

High-throughput

0.536

High

528652

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.536

High

595519

GRAH
Granzyme H

1

2

High-throughput

0.536

High

611210

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

1

High-throughput

0.536

High

708227

ECM29
Proteasome adapter and scaffold protein ECM29

1

1

High-throughput

0.536

High

708244

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

4

High-throughput

0.536

High

708255

GINM1
Glycoprotein integral membrane protein 1

1

1

High-throughput

0.536

High

708257

TSP50
Probable threonine protease PRSS50

1

1

High-throughput

0.536

High

708220

SERC3
Serine incorporator 3

1

1

High-throughput

0.515

High

245316

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.513

High

391339

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

0

High-throughput

0.513

High

394206

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.513

High

486997

LYAG
Lysosomal alpha-glucosidase

1

0

High-throughput

0.513

High

708215

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.513

High

708216

PLP2
Proteolipid protein 2

1

0

High-throughput

0.513

High

708218

SBP1
Methanethiol oxidase

1

0

High-throughput

0.513

High

708226

CAHM4
Calcium homeostasis modulator protein 4

1

0

High-throughput

0.513

High

708233

GDPD3
Lysophospholipase D GDPD3

1

0

High-throughput

0.513

High

708238

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.513

High

708240

F174A
Membrane protein FAM174A

1

0

High-throughput

0.513

High

708251

WDR11
WD repeat-containing protein 11

1

0

High-throughput

0.513

High

708259

NEUR2
Sialidase-2

1

0

High-throughput

0.513

High

435556

IGF1R
Insulin-like growth factor 1 receptor

1

2

High-throughput

0.501

High

441445

MET
Hepatocyte growth factor receptor

1

2

High-throughput

0.501

High

557047

PGFRA
Platelet-derived growth factor receptor alpha

1

1

High-throughput

0.501

High

607897

FGFR4
Fibroblast growth factor receptor 4

1

1

High-throughput

0.501

High

681687

AKT1
RAC-alpha serine/threonine-protein kinase

1

2

High-throughput

0.501

High

708203

ERD22
ER lumen protein-retaining receptor 2

1

1

High-throughput

0.501

High

708207

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

1

High-throughput

0.501

High

156800

FFAR1
Free fatty acid receptor 1

1

9

High-throughput

0.489

High

260770

H2AY
Core histone macro-H2A.1

1

1

High-throughput

0.489

High

626700

EDNRA
Endothelin-1 receptor

1

2

High-throughput

0.489

High

686268

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

4

High-throughput

0.489

High

708208

KC1E
Casein kinase I isoform epsilon

1

1

High-throughput

0.489

High

708217

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

1

High-throughput

0.489

High

708241

LRC15
Leucine-rich repeat-containing protein 15

1

1

High-throughput

0.489

High

708247

OPALI
Opalin

1

2

High-throughput

0.489

High

708252

KLK15
Kallikrein-15

1

2

High-throughput

0.489

High

708261

EPN1
Epsin-1

1

2

High-throughput

0.489

High

708205

MERL
Merlin

1

0

High-throughput

0.480

High

708223

BECN1
Beclin-1

1

0

High-throughput

0.480

High

708224

STK11
Serine/threonine-protein kinase STK11

1

0

High-throughput

0.480

High

369078

ESR1
Estrogen receptor

1

3

High-throughput

0.479

High

708204

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

166672

CE290
Centrosomal protein of 290 kDa

1

0

High-throughput

0.458

High

173560

NPHP1
Nephrocystin-1

1

0

High-throughput

0.458

High

708234

CNTRL
Centriolin

1

0

High-throughput

0.458

High

515352

CDK4
Cyclin-dependent kinase 4

1

1

High-throughput

0.457

High

665154

EPHA2
Ephrin type-A receptor 2

1

2

High-throughput

0.457

High

708206

CDN2B
Cyclin-dependent kinase 4 inhibitor B

1

1

High-throughput

0.457

High

708213

CDK6
Cyclin-dependent kinase 6

1

1

High-throughput

0.457

High

708253

LATS2
Serine/threonine-protein kinase LATS2

1

3

High-throughput

0.457

High

708256

PARP2
Poly [ADP-ribose] polymerase 2

1

1

Small-scale

0.457

High

320177

ERR2
Steroid hormone receptor ERR2

1

3

High-throughput

0.437

High

708209

MCM2
DNA replication licensing factor MCM2

1

2

High-throughput

0.437

High

708211

KS6A3
Ribosomal protein S6 kinase alpha-3

1

2

High-throughput

0.437

High

131876

UPK2
Uroplakin-2

1

0

High-throughput

0.279

Low

207222

TNF14
Tumor necrosis factor ligand superfamily member 14

1

0

High-throughput

0.279

Low

282833

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

0

High-throughput

0.279

Low

304922

DUS14
Dual specificity protein phosphatase 14

1

0

High-throughput

0.279

Low

470282

H2A1
Histone H2A type 1

1

0

High-throughput

0.279

Low

546820

PPAP
Prostatic acid phosphatase

1

0

High-throughput

0.279

Low

558995

H15
Histone H1.5

1

0

High-throughput

0.279

Low

648466

CALL3
Calmodulin-like protein 3

1

0

High-throughput

0.279

Low

702328

TNFL8
Tumor necrosis factor ligand superfamily member 8

1

0

High-throughput

0.279

Low

707355

S10A3
Protein S100-A3

1

0

High-throughput

0.279

Low

708210

PLCD1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1

1

0

High-throughput

0.279

Low

708221

PKP1
Plakophilin-1

1

0

High-throughput

0.279

Low

708222

TRI29
Tripartite motif-containing protein 29

1

0

High-throughput

0.279

Low

708225

EIPR1
EARP and GARP complex-interacting protein 1

1

0

High-throughput

0.279

Low

708228

F91A1
Protein FAM91A1

1

0

High-throughput

0.279

Low

708229

HPHL1
Ferroxidase HEPHL1

1

0

High-throughput

0.279

Low

708230

MZT2B
Mitotic-spindle organizing protein 2B

1

0

High-throughput

0.279

Low

708235

LYG2
Lysozyme g-like protein 2

1

0

High-throughput

0.279

Low

708236

DSG4
Desmoglein-4

1

0

High-throughput

0.279

Low

708242

PPM1E
Protein phosphatase 1E

1

0

High-throughput

0.279

Low

708250

LST8
Target of rapamycin complex subunit LST8

1

0

High-throughput

0.279

Low

708258

PADI3
Protein-arginine deiminase type-3

1

0

High-throughput

0.279

Low

708260

CRBG1
Beta/gamma crystallin domain-containing protein 1

1

0

High-throughput

0.279

Low

346064

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.261

Low

555085

CD44
CD44 antigen

1

0

High-throughput

0.261

Low

673025

CCND2
G1/S-specific cyclin-D2

1

0

High-throughput

0.261

Low

708219

GRM1
Metabotropic glutamate receptor 1

1

0

High-throughput

0.261

Low

708243

KAT2A
Histone acetyltransferase KAT2A

1

0

High-throughput

0.261

Low

708249

TTYH2
Protein tweety homolog 2

1

0

High-throughput

0.261

Low

708254

RASF1
Ras association domain-containing protein 1

1

0

High-throughput

0.261

Low

214115

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.249

Low

422353

NFM
Neurofilament medium polypeptide

1

0

High-throughput

0.249

Low

708214

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.249

Low

708231

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

0

High-throughput

0.249

Low

708232

BCOR
BCL-6 corepressor

1

0

High-throughput

0.249

Low

708237

ZC3C1
Zinc finger C3HC-type protein 1

1

0

High-throughput

0.249

Low

708239

POC5
Centrosomal protein POC5

1

0

High-throughput

0.249

Low

708245

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.249

Low

708246

BROMI
Protein broad-minded

1

0

Small-scale

0.249

Low

708248

FMNL2
Formin-like protein 2

1

0

High-throughput

0.249

Low

708212

MFAP4
Microfibril-associated glycoprotein 4

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024