HitPredict

Interactor 1: GCR (P04150)
Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1)
Gene: NR3C1

Interactor 2: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.27	0.60	0.408

Property	Details
Experiments	18160712
Identification Methods	unspecified method
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 777 Hs			1 536
+	Hs
		377007 GCR_HUMAN (1-777): 0: 933: 100.00		FYN_HUMAN (1-536): 0: 598: 68.39
+	Hs
		377006 GCR_HUMAN (1-777): 0: 933: 100.00		LCK_HUMAN (75-534): 0: 552: 58.48
+	Hs
		368894 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		SRC_HUMAN (1-536): 0: 651: 100.00
+	Mm
		403414 ESR1_MOUSE (263-760): 2.73e-126: 391: 22.51		SRC_MOUSE (1-536): 0: 650: 98.13
+	Rn
		411266 ESR1_RAT (263-760): 3.28e-128: 396: 22.66		SRC_RAT (1-536): 0: 644: 97.95
+	Hs
		522762 RXRA_HUMAN (292-759): 1.24e-123: 380: 21.14		SRC_HUMAN (1-536): 0: 651: 100.00
+	Hs
		414427 PRGR_HUMAN (232-777): 2.39e-110: 359: 40.00		SRC_HUMAN (1-536): 0: 651: 100.00
+	Hs
		368834 ESR1_HUMAN (263-760): 1.11e-129: 400: 23.06		YES_HUMAN (1-536): 0: 604: 73.85
+	Hs
		523091 ESR2_HUMAN (286-769): 2.89e-107: 339: 21.34		SRC_HUMAN (1-536): 0: 651: 100.00
+	Hs
		487890 RARA_HUMAN (316-759): 1.61e-105: 333: 19.60		SRC_HUMAN (1-536): 0: 651: 100.00
+	Hs
		487088 ANDR_HUMAN (357-777): 2.54e-100: 332: 45.15		SRC_HUMAN (1-536): 0: 651: 100.00
+	Hs
		433435 ESR2_HUMAN (286-769): 2.89e-107: 339: 21.34		YES_HUMAN (1-536): 0: 604: 73.85
+	Hs
		433225 ANDR_HUMAN (357-777): 2.54e-100: 332: 45.15		YES_HUMAN (1-536): 0: 604: 73.85
+	Hs
		454790 ANDR_HUMAN (357-777): 2.54e-100: 332: 45.15		FGR_HUMAN (1-535): 0: 583: 65.99
+	Hs
		442764 ANDR_HUMAN (357-777): 2.54e-100: 332: 45.15		HCK_HUMAN (1-531): 0: 569: 55.22
+	Hs
		411564 ANDR_HUMAN (357-777): 2.54e-100: 332: 45.15		LCK_HUMAN (75-534): 0: 552: 58.48
+	Hs
		433537 ANDR_HUMAN (357-777): 2.54e-100: 332: 45.15		LYN_HUMAN (1-531): 0: 532: 52.44
+	Hs
		487245 ANDR_HUMAN (357-777): 2.54e-100: 332: 45.15		BLK_HUMAN (45-531): 1.62e-179: 516: 57.58
+	Hs
		487203 ANDR_HUMAN (357-777): 2.54e-100: 332: 45.15		ABL2_HUMAN (11-536): 3.03e-170: 514: 39.03
+	Hs
		337320 ANDR_HUMAN (357-777): 2.54e-100: 332: 45.15		ABL1_HUMAN (47-536): 5.59e-169: 509: 40.00