Protein: E2F1
Transcription factor E2F1 (E2F-1)

Gene: E2F1
Organism: Mus musculus
Interactions: 28
UniProt ID: Q61501

Gene Ontology (top 5):
GO:0000077 - DNA damage checkpoint signaling
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000228 - nuclear chromosome
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

561645

RB
Retinoblastoma-associated protein

3

20

Small-scale

0.829

High

670121

NECD
Necdin

3

6

Small-scale

0.685

High

1222801

NSE3
Non-structural maintenance of chromosomes element 3 homolog

2

6

Small-scale

0.640

High

104418

F6QG91
Transcription factor

1

20

High-throughput

0.621

High

1064613

TFDP1
Transcription factor Dp-1

1

20

Small-scale

0.618

High

313411

SP1
Transcription factor Sp1

2

9

Small-scale

0.611

High

408

A0A087WPU8
Transcription factor

1

20

High-throughput

0.590

High

148698

HDAC1
Histone deacetylase 1

2

6

Small-scale

0.586

High

1222803

HTRA2
Serine protease HTRA2, mitochondrial

1

0

Small-scale

0.554

High

908679

CCNA2
Cyclin-A2

1

9

Small-scale

0.501

High

98010

ARI1B
AT-rich interactive domain-containing protein 1B

1

14

Small-scale

0.479

High

107074

F8VPR5
histone acetyltransferase

1

13

Small-scale

0.479

High

147419

BIN1
Myc box-dependent-interacting protein 1

1

3

Small-scale

0.479

High

373688

MYC
Myc proto-oncogene protein

1

8

Small-scale

0.479

High

377076

COLI
Pro-opiomelanocortin

1

1

Small-scale

0.479

High

536222

PARP1
Poly [ADP-ribose] polymerase 1

1

5

Small-scale

0.479

High

840622

PURA
Transcriptional activator protein Pur-alpha

1

1

Small-scale

0.479

High

1045973

TF65
Transcription factor p65

1

3

Small-scale

0.479

High

1189436

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

8

Small-scale

0.479

High

1222799

TOPB1
DNA topoisomerase 2-binding protein 1

1

7

Small-scale

0.479

High

1222800

Q921K2
Poly [ADP-ribose] polymerase

1

5

Small-scale

0.479

High

1222802

KAT2A
Histone acetyltransferase KAT2A

1

12

Small-scale

0.479

High

1222805

GSK3B
Glycogen synthase kinase-3 beta

1

10

Small-scale

0.479

High

1222806

SKP2
S-phase kinase-associated protein 2

1

4

Small-scale

0.479

High

642186

TAP1
Antigen peptide transporter 1

1

1

Small-scale

0.437

High

782992

TAP2
Antigen peptide transporter 2

1

1

Small-scale

0.437

High

1222798

Q6ZPV5
MKIAA1235 protein

1

7

Small-scale

0.437

High

1222804

TPSN
Tapasin

1

1

Small-scale

0.437

High


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Last updated: 11Aug2025