HitPredict

Interactor 1: PRIO (P04156)
Major prion protein (PrP) (ASCR) (PrP27-30) (PrP33-35C) (CD antigen CD230)
Gene: PRNP

Interactor 2: AT2B1 (P20020)
Plasma membrane calcium-transporting ATPase 1 (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 1) (PMCA1) (Plasma membrane calcium pump isoform 1)
Gene: ATP2B1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	29791485
Identification Methods	affinity chromatography technology
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0043231 - intracellular membrane-bounded organelle GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 253 Hs			1 1220
+	Mm
		392795 PRIO_MOUSE (1-253): 1.74e-137: 388: 89.02		AT2B2_MOUSE (1-1220): 0: 1241: 80.34
+	Hs
		377879 PRIO_HUMAN (1-253): 1.69e-164: 456: 100.00		AT1A1_HUMAN (41-1082): 0: 770: 22.46
+	Hs
		377904 PRIO_HUMAN (1-253): 1.69e-164: 456: 100.00		AT1A3_HUMAN (35-1082): 0: 761: 22.15
+	Hs
		377992 PRIO_HUMAN (1-253): 1.69e-164: 456: 100.00		AT1A2_HUMAN (40-1082): 0: 758: 22.71
+	Mm
		392787 PRIO_MOUSE (1-253): 1.74e-137: 388: 89.02		AT1A1_MOUSE (40-1082): 0: 772: 22.44
+	Mm
		392778 PRIO_MOUSE (1-253): 1.74e-137: 388: 89.02		AT1A3_MOUSE (38-1082): 0: 759: 22.21