HitPredict

Interactor 1: IFNA5 (P01569)
Interferon alpha-5 (IFN-alpha-5) (Interferon alpha-61) (Interferon alpha-G) (LeIF G)
Gene: IFNA5

Interactor 2: ISG15 (P05161)
Ubiquitin-like protein ISG15 (Interferon-induced 15 kDa protein) (Interferon-induced 17 kDa protein) (IP17) (Ubiquitin cross-reactive protein) (hUCRP)
Gene: ISG15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0051607 - defense response to virus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 165
+	Hs
		420236 IFNA4_HUMAN (1-189): 7.73e-104: 298: 83.60		ISG15_HUMAN (1-165): 4.03e-49: 157: 100.00
+	Hs
		378260 IFN10_HUMAN (1-189): 2.01e-103: 296: 82.54		ISG15_HUMAN (1-165): 4.03e-49: 157: 100.00
+	Hs
		378279 IFN21_HUMAN (1-189): 1.44e-102: 295: 86.77		ISG15_HUMAN (1-165): 4.03e-49: 157: 100.00
+	Hs
		378226 IFNA1_HUMAN (1-189): 4.13e-102: 293: 84.13		ISG15_HUMAN (1-165): 4.03e-49: 157: 100.00
+	Hs
		378324 IFN14_HUMAN (1-189): 2.21e-101: 291: 84.66		ISG15_HUMAN (1-165): 4.03e-49: 157: 100.00
+	Hs
		378268 IFNA7_HUMAN (1-189): 8.69e-101: 290: 79.89		ISG15_HUMAN (1-165): 4.03e-49: 157: 100.00
+	Hs
		378286 IFN21_HUMAN (1-189): 1.44e-102: 295: 86.77		OASL_HUMAN (3-163): 1.26e-39: 141: 24.39
+	Hs
		378247 IFNA2_HUMAN (1-189): 5.27e-96: 278: 83.60		ISG15_HUMAN (1-165): 4.03e-49: 157: 100.00
+	Hs
		425343 IFNA8_HUMAN (1-189): 2.92e-96: 278: 82.01		ISG15_HUMAN (1-165): 4.03e-49: 157: 100.00
+	Hs
		378335 IFN14_HUMAN (1-189): 2.21e-101: 291: 84.66		OASL_HUMAN (3-163): 1.26e-39: 141: 24.39
+	Hs
		746549 IFNA8_HUMAN (1-189): 2.92e-96: 278: 82.01		OASL_HUMAN (3-163): 1.26e-39: 141: 24.39
+	Hs
		420227 IFNW1_HUMAN (12-189): 1.69e-82: 244: 57.30		ISG15_HUMAN (1-165): 4.03e-49: 157: 100.00